tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate

Base Information

• Chemical Name: tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate
• CAS No.: 469890-01-5
• Molecular Formula: C₁₂H₁₉BrO₆P₂
• Molecular Weight: 401.131
• Mol file: 469890-01-5.mol

Synonyms:tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate

Chemical Property of tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate

There total 2 articles about tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-bromo-3,5-bis(bromomethyl)benzene (51760-23-7) + phosphorous acid trimethyl ester (121-45-9) → tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate (469890-01-5)

Guidance literature:

for 16h; Inert atmosphere; Reflux;

DOI:10.1021/cm2004648

Reference yield:

5-bromo-1,3-xylene (556-96-7) → tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate (469890-01-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NBS; AIBN / CH₂Cl₂

2: 87 percent / 8 h / Heating

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In dichloromethane;

DOI:10.1021/ja012694x

Reference yield: 85.0%

Dodecanal (112-54-9) + tetramethyl [(5-bromo-1,3-phenylene)bis-(methylene)]bis-phosphonate (469890-01-5) → 1-bromo-3,5-di-n-tridecenyl-benzene (1312229-45-0)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 16h; Inert atmosphere; Reflux;

DOI:10.1021/cm2004648

upstream raw materials:

1-bromo-3,5-bis(bromomethyl)benzene

phosphorous acid trimethyl ester

5-bromo-1,3-xylene

Downstream raw materials:

1-bromo-3,5-di-n-tridecenyl-benzene

1-bromo-3,5-di-n-tridecyl-benzene

3,5-di-n-tridecyl-benzaldehyde

[5,15-bis(3,5-di-n-tridecylphenyl)-porphyrinato(2-)-κN21,κN22,κN23,κN24] zinc(II)