1-(Diphenylmethyl)-4-methoxybenzene

Base Information

• Chemical Name: 1-(Diphenylmethyl)-4-methoxybenzene
• CAS No.: 13865-56-0
• Molecular Formula: C20H18O
• Molecular Weight: 274.362
• European Community (EC) Number: 660-020-6
• NSC Number: 83188
• DSSTox Substance ID: DTXSID30292491
• Nikkaji Number: J264.297B
• Wikidata: Q82030815
• Mol file: 13865-56-0.mol

Synonyms:1-(diphenylmethyl)-4-methoxybenzene;13865-56-0;1-benzhydryl-4-methoxybenzene;4-METHOXYTRIPHENYLMETHANE;((4-Methoxyphenyl)methylene)dibenzene;1-Benzhydryl-4-methoxy-benzene;NSC83188;NCIOpen2_005285;SCHEMBL34971;DTXSID30292491;1-(4-Methoxyphenyl)diphenylmethane;NSC-83188;AKOS003263006;CS-0337470;A810201

Chemical Property of 1-(Diphenylmethyl)-4-methoxybenzene

Chemical Property:

• Vapor Pressure: 4.79E-06mmHg at 25°C
• Melting Point: 66-67 °C
• Boiling Point: 393.6°C at 760 mmHg
• Flash Point: 158.9°C
• PSA: 9.23000
• Density: 1.068g/cm³
• LogP: 4.87540
• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 274.135765193
• Heavy Atom Count: 21
• Complexity: 262

Purity/Quality:

99% ^*data from raw suppliers

4-METHOXYTRIPHENYLMETHANE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=CC=C3
• Uses: 4-Methoxytriphenylmethane is used in the method of manufacturing of liquid crystal display device.4-Methoxytriphenylmethane is also used in the method for preparing polynucleotide-poly(diol) conjugates for therapeutic use.

Technology Process of 1-(Diphenylmethyl)-4-methoxybenzene

There total 79 articles about 1-(Diphenylmethyl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-chloromethoxybenzene (623-12-1) + Diphenylmethane (101-81-5) → 1-(4-methoxyphenyl)diphenylmethane (13865-56-0)

Guidance literature:

With palladium diacetate; potassium hexamethylsilazane; nixantphos; In tetrahydrofuran; at 80 ℃; for 12h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ja411855d

Reference yield: 98.0%

1,1-Diphenylmethanol (91-01-0) + methoxybenzene (100-66-3) → 1-(4-methoxyphenyl)diphenylmethane (13865-56-0)

Guidance literature:

With (diethylamino)difluorosulfonium tetrafluoroborate; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c4ob02655a

Reference yield: 97.0%

4-methoxyphenylboronic acid (5720-07-0) + diphenylmethyl methyl carbonate (85926-25-6) → 1-(4-methoxyphenyl)diphenylmethane (13865-56-0)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); 1,5-bis-(diphenylphosphino)pentane; potassium carbonate; In tert-Amyl alcohol; at 100 ℃; for 48h; Inert atmosphere;

DOI:10.1021/ol800078j

upstream raw materials:

formic acid

p-methoxytrityl alcohol

2,2-diphenyl-2-(p-methoxyphenyl)acetaldehyde

1,1-Diphenylmethanol

Downstream raw materials:

4-Methoxybenzophenone

benzophenone

(3-bromo-4-methoxyphenyl)diphenylmethanol

((3-bromo-4-methoxyphenyl)methylene)dibenzene

Refernces

• 1、 West et al.. "". . p. 267,269. Retrieved 1969.
• 2、 Yoshimura, Satoru,Nishimoto, Yoshihiro,Kiuchi, Masato,Yasuda, Makoto. "Indium implantation onto zeolite by pulse arc plasma process for the development of novel catalysts". . p. 1292 - 1294. Retrieved 2015.
• 3、 Dardir, Amira H.,Casademont-Reig, Irene,Balcells, David,Ellefsen, Jonathan D.,Espinosa, Matthew R.,Hazari, Nilay,Smith, Nicholas E.. "Synthesis of Triarylmethanes via Palladium-Catalyzed Suzuki-Miyaura Reactions of Diarylmethyl Esters". . p. 2332 - 2344. Retrieved 2021/06/28.
• 4、 Rafiee, Ezzat,Joshaghani, Mohammad,Abadi, Parvaneh Ghaderi-Shekhi. "Unmodified Fe3O4 nanostructure promoted with external magnetic field: safe, magnetically recoverable, and efficient nanocatalyst for N- and C-alkylation reactions in green conditions". . p. 2503 - 2522. Retrieved 2018/01/04.