(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

Base Information

Chemical Name:(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid
CAS No.:1418200-13-1
Molecular Formula:C₁₉H₁₈N₄O₆S
Molecular Weight:430.441
Hs Code.:

Synonyms:(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

Suppliers and Price of (1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

There total 1 articles about (1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1245649-52-8
1-(benzenesulfonyl)-4-chloro-5-nitro-1H-pyrrolo[2,3-b]pyridine

: 71830-07-4
(1S,3R)-3-aminocyclopentanecarboxylic acid

: 1418200-13-1
(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In ethanol; at 80 ℃; for 3h;

Reference yield: 96.0%

: 67-56-1
methanol

: 1418200-13-1
(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

: 1418200-14-2
(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid methyl ester

Guidance literature:: With thionyl chloride; at 60 ℃; for 1h;

Reference yield:

: 1418200-13-1
(1S,3R)-3-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-cyclopentanecarboxylic acid

: 1418200-02-8
(1S,3R)-3-(6-benzenesulfonyl-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6H-1,3,5,6-tetraaza-as-indacen-1-yl)-cyclopentanecarbaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1.1: thionyl chloride / 1 h / 60 °C

2.1: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C

3.1: triethyloxonium fluoroborate / tetrahydrofuran / 1 h / 20 °C

3.2: 3 h / 90 °C

4.1: 1H-imidazole / dichloromethane / 20 °C

5.1: sodium tetrahydroborate / ethanol / 1 h / 20 °C

6.1: Dess-Martin periodane / dichloromethane / 0 - 20 °C

With 1H-imidazole; sodium tetrahydroborate; thionyl chloride; palladium 10% on activated carbon; hydrogen; triethyloxonium fluoroborate; Dess-Martin periodane; In tetrahydrofuran; ethanol; dichloromethane;