(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Base Information

Chemical Name:(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride
CAS No.:719308-47-1
Molecular Formula:C₁₆H₂₀N₂O₃*ClH
Molecular Weight:324.807
Hs Code.:

Synonyms:(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Suppliers and Price of (2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

There total 8 articles about (2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 719308-31-3
(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid ethyl ester hydrochloride

: 78-83-1
2-methyl-propan-1-ol

: 719308-47-1
(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Guidance literature:: In toluene; at 70 ℃; for 18h; Azeotropic distillation;

Reference yield:

: (S)-2-Benzyloxycarbonylamino-succinic acid 1-ethyl ester; compound with dicyclohexyl-amine

: 719308-47-1
(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Guidance literature:: Multi-step reaction with 7 steps

1: sulfuric acid; water / diethyl ether / 18 h / Heating / reflux

2: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 18 h / 20 °C

3: triethylamine / dichloromethane / 4 h / 0 - 20 °C

4: trichlorophosphate / toluene / 1.5 h / 100 °C

5: hydrogen bromide; acetic acid / 1 h / 20 °C

6: hydrogenchloride / diethyl ether

7: toluene / 18 h / 70 °C / Azeotropic distillation

With hydrogenchloride; thionyl chloride; sulfuric acid; water; hydrogen bromide; acetic acid; triethylamine; trichlorophosphate; N,N-dimethyl-formamide; In diethyl ether; dichloromethane; toluene;

Reference yield:

: 4668-43-3
(S)-3-(benzyloxycarbonylamino)-4-ethoxy-4-oxobutanoic acid

: 719308-47-1
(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid isobutyl ester hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 18 h / 20 °C

2: triethylamine / dichloromethane / 4 h / 0 - 20 °C

3: trichlorophosphate / toluene / 1.5 h / 100 °C

4: hydrogen bromide; acetic acid / 1 h / 20 °C

5: hydrogenchloride / diethyl ether

6: toluene / 18 h / 70 °C / Azeotropic distillation

With hydrogenchloride; thionyl chloride; hydrogen bromide; acetic acid; triethylamine; trichlorophosphate; N,N-dimethyl-formamide; In diethyl ether; dichloromethane; toluene;