N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Base Information

Chemical Name:N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide
CAS No.:1433663-66-1
Molecular Formula:C₁₅H₁₄N₂O₄
Molecular Weight:286.287
Hs Code.:

Synonyms:N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Suppliers and Price of N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

There total 5 articles about N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 64-18-6
formic acid

: 1433663-62-7
3-(4-amino-3-methoxyphenyl)-5,6-dihydrobenzo[d]isoxazol-7(4H)-one

: 1433663-66-1
N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Guidance literature:: formic acid; With acetic anhydride; for 1h; Inert atmosphere; Cooling;

3-(4-amino-3-methoxyphenyl)-5,6-dihydrobenzo[d]isoxazol-7(4H)-one; In tetrahydrofuran; for 2h; Inert atmosphere; Cooling;
DOI:10.1021/acsmedchemlett.7b00178

Reference yield:

: 704-13-2
5-formyl-2-nitrophenol

: 1433663-66-1
N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / N,N-dimethyl-formamide

2: hydroxylamine hydrochloride / ethanol; water / 20 °C

3: N-chloro-succinimide / N,N-dimethyl-formamide / 15.25 h / 0 - 20 °C

4: tin(ll) chloride; ethanol / 2 h / 20 - 55 °C

5: acetic anhydride / 1 h / Cooling

With N-chloro-succinimide; ethanol; hydroxylamine hydrochloride; acetic anhydride; potassium carbonate; tin(ll) chloride; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

: 80410-57-7
3-methoxy-4-nitrobenzaldehyde

: 1433663-66-1
N-(2-methoxy-4-(7-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)phenyl)formamide

Guidance literature:: Multi-step reaction with 4 steps

1: hydroxylamine hydrochloride / ethanol; water / 20 °C

2: N-chloro-succinimide / N,N-dimethyl-formamide / 15.25 h / 0 - 20 °C

3: tin(ll) chloride; ethanol / 2 h / 20 - 55 °C

4: acetic anhydride / 1 h / Cooling

With N-chloro-succinimide; ethanol; hydroxylamine hydrochloride; acetic anhydride; tin(ll) chloride; In ethanol; water; N,N-dimethyl-formamide;