Technology Process of C31H25ClFN3O4
There total 9 articles about C31H25ClFN3O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
phosgene; 4-{[7-(Benzyloxy)-6-methoxy-4-quinolyl]oxy}-2-chloroaniline;
With
triethylamine;
In
dichloromethane; toluene;
at -78 - 20 ℃;
for 1.5h;
3-amino-4-fluorotoluene;
In
dichloromethane; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 45 °C
2: potassium carbonate; sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 100 °C / Inert atmosphere
3: triethylamine / dichloromethane; toluene / 1.5 h / -78 - 20 °C
With
sodium hydride; potassium carbonate; triethylamine;
In
dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: trichlorophosphate / 10 h / Reflux
2: potassium carbonate; sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 100 °C / Inert atmosphere
3: triethylamine / dichloromethane; toluene / 1.5 h / -78 - 20 °C
With
sodium hydride; potassium carbonate; triethylamine; trichlorophosphate;
In
dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;