(3β)-3-(tert-ButyldiMethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester

Base Information

Chemical Name:(3β)-3-(tert-ButyldiMethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester
CAS No.:114011-35-7
Molecular Formula:C₃₁H₅₄O₃Si
Molecular Weight:502.853
Hs Code.:
Mol file:114011-35-7.mol

Synonyms:3β-(t-butyldimethylsilyloxy)-5-cholenic acid methyl ester

Suppliers and Price of (3β)-3-(tert-ButyldiMethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3β)-3-(tert-Butyldimethylsilyl)oxy-chol-5-en-24-oicAcidMethylEster
25mg
$ 145.00

Medical Isotopes, Inc.
(3β)-3-(tert-Butyldimethylsilyl)oxy-chol-5-en-24-oicAcidMethylEster
250 mg
$ 2120.00

Total 1 raw suppliers

Chemical Property of (3β)-3-(tert-ButyldiMethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester

Chemical Property:

Melting Point:157-160oC
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:: (3β)-3-(tert-Butyldimethylsilyl)oxy-chol-5-en-24-oicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (3β)-3-(tert-Butyldimethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester is an intermediate in the preparation of steroidal antitumor compounds.

Technology Process of (3β)-3-(tert-ButyldiMethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester

There total 16 articles about (3β)-3-(tert-ButyldiMethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 67-56-1
methanol

: 5255-17-4
3β-hydroxy-5-cholenoic acid

: 18162-48-6
tert-butyldimethylsilyl chloride

: 114011-35-7
3β-(t-butyldimethylsilyloxy)-5-cholenic acid methyl ester

Guidance literature:: methanol; 3β-hydroxy-5-cholenoic acid; With toluene-4-sulfonic acid; at 60 ℃;

tert-butyldimethylsilyl chloride; With 1H-imidazole; dmap; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield: 97.0%

: 20231-57-6
methyl 5-cholenoate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 114011-35-7
3β-(t-butyldimethylsilyloxy)-5-cholenic acid methyl ester

Guidance literature:: With pyridine; 1H-imidazole; In N,N-dimethyl-formamide; at 25 ℃; for 1.5h; Inert atmosphere;
DOI:10.1016/j.bmc.2015.03.053