Disodium EDTA

Base Information

• Chemical Name: Disodium EDTA
• CAS No.: 139-33-3
• Molecular Formula: C10H14N2Na2O8
• Molecular Weight: 336.209
• Hs Code.: 29224999
• European Community (EC) Number: 205-358-3,230-944-0,613-386-6,680-249-5
• NSC Number: 759604,756746,2760
• NCI Thesaurus Code: C61741
• RXCUI: 3539
• Mol file: 139-33-3.mol

Synonyms:Acid, Edetic;Acid, Ethylenediaminetetraacetic;Acid, Ethylenedinitrilotetraacetic;Calcitetracemate, Disodium;Calcium Disodium Edetate;Calcium Disodium Versenate;Calcium Tetacine;Chelaton 3;Chromium EDTA;Copper EDTA;Coprin;Dicobalt EDTA;Dinitrilotetraacetate, Disodium Ethylene;Dinitrilotetraacetate, Ethylene;Disodium Calcitetracemate;Disodium EDTA;Disodium Ethylene Dinitrilotetraacetate;Disodium Versenate, Calcium;Distannous EDTA;Edathamil;Edetate Disodium Calcium;Edetate, Calcium Disodium;Edetates;Edetic Acid;Edetic Acid, Calcium Salt;Edetic Acid, Calcium, Sodium Salt;Edetic Acid, Chromium Salt;Edetic Acid, Dipotassium Salt;Edetic Acid, Disodium Salt;Edetic Acid, Disodium Salt, Dihydrate;Edetic Acid, Disodium, Magnesium Salt;Edetic Acid, Disodium, Monopotassium Salt;Edetic Acid, Magnesium Salt;Edetic Acid, Monopotassium Salt;Edetic Acid, Monosodium Salt;Edetic Acid, Potassium Salt;Edetic Acid, Sodium Salt;EDTA;EDTA, Chromium;EDTA, Copper;EDTA, Dicobalt;EDTA, Disodium;EDTA, Distannous;EDTA, Gallium;EDTA, Magnesium Disodium;EDTA, Potassium;EDTA, Stannous;Ethylene Dinitrilotetraacetate;Ethylene Dinitrilotetraacetate, Disodium;Ethylenediaminetetraacetic Acid;Ethylenedinitrilotetraacetic Acid;Gallium EDTA;Magnesium Disodium EDTA;N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine);Potassium EDTA;Stannous EDTA;Tetacine, Calcium;Tetracemate;Versenate;Versenate, Calcium Disodium;Versene

Chemical Property of Disodium EDTA

Chemical Property:

• Appearance/Colour: white crystalline solid
• Vapor Pressure: 1.15E-16mmHg at 25°C
• Melting Point: 248 °C (dec.)(lit.)
• Boiling Point: >100°C
• Flash Point: 325.2oC
• PSA: 161.34000
• Density: 1.01 g/mL at 25 °C
• LogP: -4.74060
• Storage Temp.: 2-8°C
• Solubility.: H2O: clear, colorless
• Water Solubility.: Miscible with water.
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 11
• Exact Mass: 315.08043475
• Heavy Atom Count: 21
• Complexity: 316

Purity/Quality:

99% ^*data from raw suppliers

EthylenediaminetetraaceticAcidDisodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,C
• Statements: 36/38-36/37/38-22-34-21/22
• Safety Statements: 26-36-37/39-45-36/37/39-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Uses -> Chelating Agents
• Canonical SMILES: C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O.[Na+]
• Recent ClinicalTrials: Trial to Assess Chelation Therapy 2
• Description: Ethylenediaminetetra-acetic acid (abbreviated as EDTA) is used in several industrial applications attributing to its high ability to bind to most of metal cations. EDTA is produced as several salts, e.g. ethylenediaminetetra-acetic acid disodium salt (EDTAS). EDTA and its salts are used as chelating agents in cosmetic formulations. EDTAS is a preservative, sequestrant, and stabilizer in foods. EDTA is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene. EDTA and its salts are used as a component in the production of food-contact paper and paperboard. EDTAS is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals. In the textile industry, EDTA and its salts prevent metal ion impurities from changing colors of dyed products. In the pulp and paper industry, EDTA and its salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent). EDTAS is used in synthetic rubber manufacture. EDTAS is also used as a corrosion inhibitor to carbon steel in the industries. As an anticoagulant, EDTAS and tripotassium salts of EDTA are most commonly used.
• uses: Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.
• Uses: disodium EDTA is a preservative used in concentrations of 0.1 to 0.5 percent. Disodium Dihydrogen EDTA is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate. it is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels. A 1% solution has a ph of 4.3–4.7. It is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation. Its function is comparable to that of disodium calcium edta. Chelating agent (metal); pharmaceutic aid (chelating agent). Ethylenediaminetetraacetic acid disodium salt is widely used in textile industry. Usually applied to dissolve limescale. It is applied in textile industry, pulp and paper industry and also in chelation therapy. In cosmetics, it acts as a sequestering agent. It acts as a corrosion inhibitor to carbon steel in the industries. It also acts as a food additive.
• Therapeutic Function: Pharmaceutic aid (chelating agent)

Technology Process of Disodium EDTA

There total 12 articles about Disodium EDTA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ mannitol (69-65-8) + edetate disodium (139-33-3)

Guidance literature:

Reference yield:

ethylenediaminetetraacetic acid (60-00-4,94108-75-5) → disodium ethylenediamine tetraacetic acid (64-02-8,139-33-3,150-38-9,7379-28-4,17421-79-3,71705-16-3,116229-67-5)

Guidance literature:

With sodium hydroxide; In water; at 90 - 95 ℃; for 0.75h; pH=5;

Reference yield:

→ disodium ethylenediamine tetraacetic acid (64-02-8,139-33-3,150-38-9,7379-28-4,17421-79-3,71705-16-3,116229-67-5)

Guidance literature:

upstream raw materials:

ethylenediaminetetraacetic acid

chloropropionic acid

ethylenediamine-N-acetic acid dihydrochloride dihydrate

chloroacetic acid

Downstream raw materials:

ethylenediamine-N,N,N'-triacetic acid

formaldehyd

formic acid

carbon dioxide

Refernces

• 1、 -. "VINYL MONOMERS HAVING CHELATING FUNCTIONALITY". Page/Page column 10-11. . Retrieved 2013/05/22.
• 2、 -. "AMINOCARBOXYLATE POWDERS WITH IMPROVED PURITY AND FLOW ABILITY PROPERTIES". Page/Page column 10-11. . Retrieved 2011/12/04.