benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Base Information

Chemical Name:benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate
CAS No.:1037834-45-9
Molecular Formula:C₂₃H₂₅ClN₂O₅
Molecular Weight:444.915
Hs Code.:

Synonyms:benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Suppliers and Price of benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Chemical Property:

Purity/Quality:: 95.0% ^*data from raw suppliers

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Technology Process of benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

There total 3 articles about benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1037834-44-8
benzyl 4-(4-(methoxycarbonyl)-phenylamino)piperidine-1-carboxylate

: 79-04-9
chloroacetyl chloride

: 1037834-45-9
benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Guidance literature:: With pyridine; In ethyl acetate; at 3 - 20 ℃; for 1.5h; Inert atmosphere;
DOI:10.15227/orgsyn.090.0074

Reference yield:

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 1037834-45-9
benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium triacetoxy borohydride; acetic acid / 1,2-dichloro-ethane / Large scale reaction

2: pyridine / ethyl acetate / 0.67 h / 15 - 25 °C / Large scale reaction

With pyridine; sodium triacetoxy borohydride; acetic acid; In ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1021/op200332p

Reference yield:

: 619-45-4
4-methoxycarbonyl aniline

: 1037834-45-9
benzyl 4-(2-chloro-N-(4-(methoxycarbonyl)phenyl)acetamido)-piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium triacetoxy borohydride; acetic acid / 1,2-dichloro-ethane / Large scale reaction

2: pyridine / ethyl acetate / 0.67 h / 15 - 25 °C / Large scale reaction

With pyridine; sodium triacetoxy borohydride; acetic acid; In ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1021/op200332p