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2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole

Base Information Edit
  • Chemical Name:2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole
  • CAS No.:152121-20-5
  • Molecular Formula:C21H13FN4O
  • Molecular Weight:356.359
  • Hs Code.:
  • Mol file:152121-20-5.mol
2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole

Synonyms:2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole

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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of 2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole Edit
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Technology Process of 2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole

There total 7 articles about 2-(4-Cyanophenyl)-4-(4-fluorophenyl)-1-N-hydroxy-5-(4-pyridyl)imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 4 steps
1: 100 percent / Et3N / CH2Cl2 / 0.5 h
2: 1.) LDA / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, from -78 deg C to RT
3: 74 percent / 3 N aq. HCl, NaNO2 / 0.5 h / Ambient temperature
4: 100 percent / NH4OAc, CH3CO2H / 18 h / Heating
With hydrogenchloride; ammonium acetate; acetic acid; triethylamine; lithium diisopropyl amide; sodium nitrite; In dichloromethane;
DOI:10.1016/S0968-0896(96)00212-X
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