(R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

Base Information

Chemical Name:(R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate
CAS No.:1600511-33-8
Molecular Formula:C₁₆H₂₁BrFNO₃S
Molecular Weight:406.316
Hs Code.:

Synonyms:(R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

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Technology Process of (R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

There total 5 articles about (R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1313525-81-3
(R)-tert-butyl 4-(5-bromo-2-fluorophenyl)-4-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

: 10387-40-3
potassium thioacetate

: 1600511-33-8
(R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

Guidance literature:: In N,N-dimethyl-formamide;

Reference yield: 44.0%

: 1313525-80-2
rac-[1-(5-bromo-2-fluoro-phenyl)-2-hydroxy-1-methyl-ethyl]-carbamic acid tert-butyl ester

: 96042-30-7
4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

: 507-09-5
tiolacetic acid

: 1600511-33-8
(R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

Guidance literature:: With diisopropyl (E)-azodicarboxylate; triphenylphosphine; In tetrahydrofuran;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1600511-33-8
(R)-S-(2-(5-Bromo-2-fluorophenyl)-2-((tert-butoxy carbonyl)amino)propyl) ethanethioate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / 1,4-dioxane; water

2: triphenylphosphine; diisopropyl (E)-azodicarboxylate / tetrahydrofuran

With sodium hydrogencarbonate; diisopropyl (E)-azodicarboxylate; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; water;