Technology Process of methyl 4-(4-bromo-3,5-dimethylphenyl)butanoate
There total 6 articles about methyl 4-(4-bromo-3,5-dimethylphenyl)butanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
water;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 1 h / 20 °C
2: methanol; sodium tetrahydroborate / 2 h / 20 °C
3: triethylamine / dichloromethane / 2 h / 20 °C
4: N,N-dimethyl-formamide / 2 h / 80 °C
5: hydrogenchloride / water / 1 h / Reflux
With
hydrogenchloride; methanol; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; triethylamine;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 0 °C
1.2: 0.5 h / 0 °C
2.1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 1 h / 20 °C
3.1: methanol; sodium tetrahydroborate / 2 h / 20 °C
4.1: triethylamine / dichloromethane / 2 h / 20 °C
5.1: N,N-dimethyl-formamide / 2 h / 80 °C
6.1: hydrogenchloride / water / 1 h / Reflux
With
hydrogenchloride; methanol; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; sodium hydride; triethylamine;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
