Phosphoramidate

Base Information

• Chemical Name: Phosphoramidate
• CAS No.: 22638-09-1
• Molecular Formula: H2N O3 P
• Molecular Weight: 94.9945
• DSSTox Substance ID: DTXSID60945302
• Nikkaji Number: J2.586.965F
• Wikidata: Q27104092
• Mol file: 22638-09-1.mol

Synonyms:phosphoramidate;phosphoramidic acid;phosphoramidic acid, sodium salt;potassium phosphoramidate

Chemical Property of Phosphoramidate

Chemical Property:

• XLogP3: -2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 94.97722992
• Heavy Atom Count: 5
• Complexity: 49.8

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: NP(=O)([O-])[O-]

Technology Process of Phosphoramidate

There total 4 articles about Phosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ammonium amidophosphate (13566-20-6) → pyrophosphate tetraanion (14000-31-8) + triphosphate (14127-68-5) + amino-phosphonate (22638-09-1) + ammonia (7664-41-7) + Phosphate (14265-44-2,264888-19-9)

Guidance literature:

With urea; In melt; byproducts: guanidinium ion; urea and NH4HPO3NH2 heated under N2 at atmosphere pressure and 120°C; not isolated; detected by paper chromy. and NMR;

DOI:10.1246/bcsj.58.3613

Reference yield:

ammonium hydroxide (1336-21-6) + phosphonic Acid (13598-36-2) → amino-phosphonate (22638-09-1) + Phosphate (14265-44-2,264888-19-9)

Guidance literature:

at 20 ℃; for 336h; UV-irradiation; Sealed tube;

DOI:10.1002/anie.201903808

Reference yield:

ammonium hydroxide (1336-21-6) + P4O10 → amino-phosphonate (22638-09-1) + diamidophosphate (22638-07-9) + Phosphate (14265-44-2,264888-19-9)

Guidance literature:

at 20 ℃; for 24h;

DOI:10.1002/anie.201903808

upstream raw materials:

ammonium amidophosphate

ammonium hydroxide

phosphonic Acid

Downstream raw materials:

ammonia

Phosphate

Refernces

• 1、 Shimasaki, Choichiro,Hara, Mitsunari. "Ueber die Reaktion von Harnstoff mit Ammoniumhydrogenamidophosphat unter dem Atmosphaerendruck". . p. 3613 - 3616. Retrieved 2007/10/02.