N-(o-chlorophenyl)formohydroxamic acid

Base Information

• Chemical Name: N-(o-chlorophenyl)formohydroxamic acid
• CAS No.: 109384-39-6
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.583
• Mol file: 109384-39-6.mol

Synonyms:N-(o-chlorophenyl)formohydroxamic acid

Chemical Property of N-(o-chlorophenyl)formohydroxamic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-(o-chlorophenyl)formohydroxamic acid

There total 3 articles about N-(o-chlorophenyl)formohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

o-Chloronitrosobenzene (932-33-2) + Glyoxilic acid (298-12-4) → N-(o-chlorophenyl)formohydroxamic acid (109384-39-6)

Guidance literature:

In acetic acid; for 17h; Ambient temperature;

DOI:10.1021/jo00279a039

Reference yield: 60.0%

2-chloro-N-hydroxybenzenamine (10468-16-3) + formyl acetic anhydride (2258-42-6) → N-(o-chlorophenyl)formohydroxamic acid (109384-39-6)

Guidance literature:

In diethyl ether; at 0 - 27 ℃; for 14h;

Reference yield: 50.0%

formic acid (64-18-6) + 2-chloro-N-hydroxybenzenamine (10468-16-3) → N-(o-chlorophenyl)formohydroxamic acid (109384-39-6)

Guidance literature:

With acetic anhydride; at 35 - 40 ℃; for 16h;

DOI:10.1055/s-1987-27847

upstream raw materials:

formic acid

2-chloro-N-hydroxybenzenamine

o-Chloronitrosobenzene

Glyoxilic acid

Downstream raw materials:

N-(2,6-dichlorophenyl)-1,1-dichloromethanimine

Clonidin