1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Base Information

Chemical Name:1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene
CAS No.:107135-61-5
Molecular Formula:C₃₃H₂₈O₄Se
Molecular Weight:567.543
Hs Code.:

Synonyms:1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Suppliers and Price of 1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

There total 11 articles about 1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13146-23-1
copper(I) phenylacetylenide

: 107135-61-5
1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / pyridine / 12 h / Heating

2: 1.) n-butyllithium / 1.) hexane, ether, -78 deg C, 20 min, 2.) hexane, ether, from -78 deg C to 0 deg C, 2 h

3: 75 percent / pyridinium chlorochromate, 3-A molecular sieves / CH₂Cl₂ / 4 h / Ambient temperature

4: 1.) LDA / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, from -78 deg C to -20 deg C, 1.5 h

With pyridine; n-butyllithium; 3 A molecular sieve; pyridinium chlorochromate; lithium diisopropyl amide; In dichloromethane;
DOI:10.1021/jo00383a032

Reference yield:

: 34985-41-6
7-methoxy-indan-1-one

: 107135-61-5
1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) potassium tert-butoxide / 1.) dioxane, RT, 1.5 h, 2.) dioxane, RT, 22 h

2: p-toluenesulfonic acid monohydrate / dioxane; H₂O / 14 h / Heating

3: 1.) n-butyllithium / 1.) hexane, ether, -78 deg C, 20 min, 2.) hexane, ether, from -78 deg C to 0 deg C, 2 h

4: 75 percent / pyridinium chlorochromate, 3-A molecular sieves / CH₂Cl₂ / 4 h / Ambient temperature

5: 1.) LDA / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, from -78 deg C to -20 deg C, 1.5 h

With n-butyllithium; 3 A molecular sieve; potassium tert-butylate; toluene-4-sulfonic acid; pyridinium chlorochromate; lithium diisopropyl amide; In 1,4-dioxane; dichloromethane; water;
DOI:10.1021/jo00383a032

Reference yield:

: 26002-57-3
2-amino-3-nitrohydroquinone dimethylether

: 107135-61-5
1-<3,6-dimethoxy-2-(phenylethynyl)benzoyl>-2,3-dihydro-7-methoxy-1-(phenylseleno)-1H-indene

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) sodium nitrite, conc. H₂SO₄, 2.) copper(I)bromide, hydrogen bromide / 1.) methanol, water, 0 deg C, 30 min, 2.) methanol, water, reflux, 1 h

2: 100 percent / activated carbon, ferric chloride hexahydrate, hydrazine hydrate / methanol / 12 h / Heating

3: 1.) sodium nitrite, conc. HCl, 2.) potassium iodide / 1.) water, 0 deg C, 20 min, 2.) water, RT, overnight

4: 78 percent / pyridine / 12 h / Heating

5: 1.) n-butyllithium / 1.) hexane, ether, -78 deg C, 20 min, 2.) hexane, ether, from -78 deg C to 0 deg C, 2 h

6: 75 percent / pyridinium chlorochromate, 3-A molecular sieves / CH₂Cl₂ / 4 h / Ambient temperature

7: 1.) LDA / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, from -78 deg C to -20 deg C, 1.5 h

With pyridine; hydrogenchloride; n-butyllithium; 3 A molecular sieve; sulfuric acid; hydrogen bromide; iron(III) chloride; pyrographite; hydrazine hydrate; pyridinium chlorochromate; potassium iodide; copper(I) bromide; lithium diisopropyl amide; sodium nitrite; In methanol; dichloromethane;
DOI:10.1021/jo00383a032