1-Piperazineethanamine, N,N,4-trimethyl-

Base Information

• Chemical Name: 1-Piperazineethanamine, N,N,4-trimethyl-
• CAS No.: 104-19-8
• Deprecated CAS: 100359-89-5,205657-41-6,880874-56-6,205657-41-6,880874-56-6
• Molecular Formula: C9H21 N3
• Molecular Weight: 171.286
• Hs Code.: 2933599090
• European Community (EC) Number: 203-183-7
• NSC Number: 79879
• UNII: 384CK0D21R
• DSSTox Substance ID: DTXSID5059292
• Nikkaji Number: J22.150C
• Wikidata: Q27256736
• Mol file: 104-19-8.mol

Synonyms:104-19-8;1-Piperazineethanamine, N,N,4-trimethyl-;N,N-dimethyl-2-(4-methylpiperazin-1-yl)ethanamine;1-(2-Dimethylaminoethyl)-4-methylpiperazine;Toyocat NP;Kaolizer 8;1-(2-(N,N-Dimethylamino)ethyl)-4-methylpiperazine;S 36081-3;NSC 79879;1-(2-(Dimethylamino)ethyl)-4-methylpiperazine;N,N,4-Trimethylpiperazine-1-ethylamine;EINECS 203-183-7;N-Methyl-N'-(beta-dimethylaminoethyl)piperazine;N-Methyl-N'-(.beta.-dimethylaminoethyl)piperazine;BRN 0106624;UNII-384CK0D21R;384CK0D21R;Piperazine, 1-(2-(dimethylamino)ethyl)-4-methyl-;NSC-79879;N,N-Dimethyl-2-(4-methylpiperazin-1-yl)ethan-1-amine;N-Methyl-N'-(dimethylaminoethyl)piperazine;1-[2-(Dimethylamino)ethyl]-4-methylpiperazine;5-23-01-00270 (Beilstein Handbook Reference);Piperazine, 1-[2-(dimethylamino)ethyl]-4-methyl-;ETHANAMINE,N,N-DIMETHYL(4-METHYL-1-PIPERAZINYL)-;NSC79879;1-Piperazineethanamine,N,N,4-trimethyl-;JEFFCAT TR 52;dimethyl[2-(4-methylpiperazin-1-yl)ethyl]amine;SCHEMBL134397;KL 8;DTXSID5059292;n,n,n'-trimethylaminoethylpiperazine;MFCD00059773;N,N,4-trimethylpiperazin-1-ethylamin;1-Piperazineethanamine,N,4-trimethyl-;AKOS022300257;1-methyl-4-dimethylaminoethylpiperazine;n-methyl-n'-dimethylaminoethylpiperazine;WLN: T6N DNTJ A2N1 & 1 D1;LS-111809;CS-0325410;D1766;FT-0605533;N-methyl-4-(2 dimethylaminoethyl)piperazine;A800920;N,N-Dimethyl-2-(4-methyl-1-piperazinyl)ethanamine;1-(2-DIMETHYL AMINOETHYL)-4-METHYLPIPERAZINE;N,N-Dimethyl-2-(4-methyl-1-piperazinyl)ethanamine #;Q27256736;S-36081-3

Chemical Property of 1-Piperazineethanamine, N,N,4-trimethyl-

Chemical Property:

• Vapor Pressure: 0.224mmHg at 25°C
• Refractive Index: 1.4630-1.4660
• Boiling Point: 207.5 °C at 760 mmHg
• PKA: 9.50±0.28(Predicted)
• Flash Point: 74.5 °C
• PSA: 9.72000
• Density: 0,89 g/cm3
• LogP: -0.32880
• Water Solubility.: Completely miscible in water
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 171.173547683
• Heavy Atom Count: 12
• Complexity: 117

Purity/Quality:

99.9% ^*data from raw suppliers

1-(2-Dimethylaminoethyl)-4-methylpiperazine >98.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCN(CC1)CCN(C)C

Technology Process of 1-Piperazineethanamine, N,N,4-trimethyl-

There total 12 articles about 1-Piperazineethanamine, N,N,4-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

aminoethylpiperazine (140-31-8) + methanol (67-56-1) → N-methyl-N'-(2-dimethylaminoethyl)piperazine (104-19-8)

Guidance literature:

With 5percent silver supported on titanium oxide; at 25 ℃; for 10h; Inert atmosphere; Sealed tube; UV-irradiation;

Reference yield:

N,N,N,N,-tetramethylethylenediamine (110-18-9) → N,N'-dimethylpiperazine (106-58-1) + N-methyl-N'-(2-dimethylaminoethyl)piperazine (104-19-8) + N-ethyl-N,N',N'-trimethylethylenediamine (106-64-9) + trimethylamine (75-50-3)

Guidance literature:

With carbon monoxide; iron pentacarbonyl; dodecacarbonyl-triangulo-triruthenium; In ethanol; at 160 ℃; for 120h; under 25857.4 - 51714.8 Torr; Further byproducts given;

DOI:10.1021/ja00288a015

Reference yield:

N,N,N,N,-tetramethylethylenediamine (110-18-9) → N,N'-dimethylpiperazine (106-58-1) + N-methyl-N'-(2-dimethylaminoethyl)piperazine (104-19-8) + N,N,N',N'',N'''-pentamethyldiethylenetriamine (3030-47-5) + N-ethyl-N,N',N'-trimethylethylenediamine (106-64-9) + trimethylamine (75-50-3)

Guidance literature:

With carbon monoxide; iron pentacarbonyl; dodecacarbonyl-triangulo-triruthenium; In ethanol; at 160 ℃; for 20h; under 25857.4 - 51714.8 Torr; Product distribution;

DOI:10.1021/ja00288a015

upstream raw materials:

1-methyl-piperazine

(2-chloroethyl)dimethylamine hydrochloride

N,N-Dimethylamino acetonitrile

mechlorethamine hydrochloride

Refernces

• 1、 -. "Amine catalyst for producing polyurethane and polyisocyanurate". . . Retrieved 2008/06/13.