Chemical Property of Nicotyrine
Chemical Property:
- Vapor Pressure:0.00561mmHg at 25°C
- Melting Point:168-169 °C
- Refractive Index:1.6057 (estimate)
- Boiling Point:282.8°Cat760mmHg
- PKA:pK1:4.76(+1) (25°C)
- Flash Point:124.8°C
- PSA：17.82000
- Density:1.04g/cm3
- LogP:2.08710
- Storage Temp.:-20°C Freezer, Under Inert Atmosphere
- Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
- XLogP3:1.3
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:1
- Exact Mass:158.084398327
- Heavy Atom Count:12
- Complexity:147
- Purity/Quality:
-
99%, *data from raw suppliers
β-Nicotyrine *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CN1C=CC=C1C2=CN=CC=C2
-
Description
The occurrence of this alkaloid in the cigar type of tobacco has been reported by
Wenusch and subsequently confirmed by Spath and Kesztler. It forms a colour_x0002_less oil when pure and yields crystalline salts and derivatives, e.g. the p1atinichloride, m.p. 158°C; picrate, m.p. 170-1 °c and the methiodide, m.p. 2l1-3°e.
It may also be prepared from nicotine by oxidation with silver oxide, silver
acetate or potassium ferricyanide. With Zn and HCI, the base is reduced to nicotine and 4:5-dihydronicotyrine, b.p. 244-6°C, yielding a dipicrate, m.p. l64°e.
In the presence of prepared Pt02, the latter may be further reduced to dihydrometanicotine, the dipicrate of which has m.p. 161-2°C. Nicotyrine may be converted directly into nicotine in one operation by controlled hydrogenation in the
presence on Pd-e
-
Uses
Nicotryrine is an alkaloid derived from the dehydrogenation of nicotine and its analog, nornicotine. An alkaloid occurring in cigaret smoke.
