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Triflupromazine

Base Information Edit
  • Chemical Name:Triflupromazine
  • CAS No.:146-54-3
  • Molecular Formula:C18H19 F3 N2 S
  • Molecular Weight:352.423
  • Hs Code.:2934300000
  • European Community (EC) Number:205-673-6
  • UNII:RO16TQF95Y
  • DSSTox Substance ID:DTXSID9023704
  • Nikkaji Number:J2.957B
  • Wikipedia:Triflupromazine
  • Wikidata:Q510494
  • NCI Thesaurus Code:C66635
  • Pharos Ligand ID:7FQT7QK7XC6B
  • Metabolomics Workbench ID:42851
  • ChEMBL ID:CHEMBL570
  • Mol file:146-54-3.mol
Triflupromazine

Synonyms:Fluopromazine;Siquil;Trifluopromazine;Triflupromazine

Suppliers and Price of Triflupromazine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • American Custom Chemicals Corporation
  • TRIFLUPROMAZINE 95.00%
  • 10MG
  • $ 255.15
Total 11 raw suppliers
Chemical Property of Triflupromazine Edit
Chemical Property:
  • Melting Point:25°C 
  • Refractive Index:nD23 1.5780 
  • Boiling Point:427.6°Cat760mmHg 
  • PKA:pKa 9.41(H2O (extrap) t = 24±1 I~0.002) (Uncertain) 
  • Flash Point:212.4°C 
  • PSA:31.78000 
  • Density:1.238g/cm3 
  • LogP:5.32480 
  • Water Solubility.:1.762mg/L(24 oC) 
  • XLogP3:5.2
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:4
  • Exact Mass:352.12210427
  • Heavy Atom Count:24
  • Complexity:416
Purity/Quality:

95-99% *data from raw suppliers

TRIFLUPROMAZINE 95.00% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F
  • Uses In psychiatric practice, triflupromazine is used for psychomotor excitement in patients with schizophrenia for paranoid and manic-depressive conditions, and for neurosis. Antipsychotic.
  • Therapeutic Function Tranquilizer
Technology Process of Triflupromazine

There total 7 articles about Triflupromazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With copper(l) iodide; potassium carbonate; L-proline; In ethyl methyl ether; at 90 - 110 ℃; Inert atmosphere;
DOI:10.1002/anie.200905646
Guidance literature:
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; In toluene; at 60 - 160 ℃; for 2.33333h; Microwave irradiation;
DOI:10.1002/anie.200705209
Guidance literature:
With formic acid; In water; at 80 ℃; for 8h; Microwave irradiation;
DOI:10.1021/acschemneuro.8b00242
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