(+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Base Information

Chemical Name:(+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
CAS No.:862129-71-3
Molecular Formula:C₁₃H₂₃BO₄S
Molecular Weight:286.2
Hs Code.:

Synonyms:(+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Suppliers and Price of (+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Methylsulfonylcyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
2.5g
$ 1320.00

Medical Isotopes, Inc.
2-(4-Methylsulfonylcyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
2.5 g
$ 2200.00

Total 3 raw suppliers

Chemical Property of (+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Methylsulfonylcyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(4-Methylsulfonylcyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane is a reactant used in the preparation of piperidine derivatives as selective estrogen receptor modulators (SERMs) for the potential treatment of uterine fibroids.

Technology Process of (+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

There total 3 articles about (+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 862129-73-5
(+/-)-trifluoro-methanesulfonic acid 4-methanesulfonyl-cyclohex-1-enyl ester

: 73183-34-3
bis(pinacol)diborane

: 862129-71-3
(+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In dimethyl sulfoxide; at 70 ℃; for 12h;

Reference yield:

: C₁₀H₂₀SO₃Si

: 862129-71-3
(+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: Multi-step reaction with 3 steps

1: TFA / methanol

2: 2,6-di-tert-butyl-4-methylpyridine / CH₂Cl₂

3: KOAc / PdCl₂(dppf)

With 2,6-di-tert-butyl-4-methylpyridine; potassium acetate; trifluoroacetic acid; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2007.04.044

Reference yield:

: 862129-72-4
4-(methylsulfonyl)cyclohexan-1-one

: 862129-71-3
(+/-)-2-(4-methanesulfonyl-cyclohex-1-enyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: Multi-step reaction with 2 steps

1: 2,6-di-tert-butyl-4-methylpyridine / CH₂Cl₂

2: KOAc / PdCl₂(dppf)

With 2,6-di-tert-butyl-4-methylpyridine; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dichloromethane;
DOI:10.1016/j.bmcl.2007.04.044