methyl (4-phenyloxy)phenyl sulfide

Base Information

• Chemical Name: methyl (4-phenyloxy)phenyl sulfide
• CAS No.: 21134-14-5
• Molecular Formula: C₁₃H₁₂OS
• Molecular Weight: 216.304
• Mol file: 21134-14-5.mol

Synonyms:methyl (4-phenyloxy)phenyl sulfide

Chemical Property of methyl (4-phenyloxy)phenyl sulfide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (4-phenyloxy)phenyl sulfide

There total 9 articles about methyl (4-phenyloxy)phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(4-bromophenyl)thioanisole (104-95-0) + phenol (108-95-2,27073-41-2) → methyl (4-phenyloxy)phenyl sulfide (21134-14-5)

Guidance literature:

With potassium phosphate; copper(l) iodide; N,N’-bis(2-phenylphenyl)oxalic acid; In acetonitrile; at 90 ℃; for 24h; Solvent; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.7b00493

Reference yield: 90.0%

4-iodothioanisole (35371-03-0) + phenol (108-95-2,27073-41-2) → methyl (4-phenyloxy)phenyl sulfide (21134-14-5)

Guidance literature:

With potassium phosphate; copper(l) iodide; N-(2-phenylphenyl)-N′-benzyl oxalamide; In acetonitrile; at 90 ℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.7b00493

Reference yield: 82.0%

2-methylmercapto-ethanol (5271-38-5) + 4-phenoxyiodobenzene (2974-94-9) → methyl (4-phenyloxy)phenyl sulfide (21134-14-5)

Guidance literature:

With potassium tert-butylate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium dichloride; In 5,5-dimethyl-1,3-cyclohexadiene; at 120 ℃; for 12h;

DOI:10.1039/c9sc05532k

upstream raw materials:

diphenylether

Dimethyldisulphide

(4-bromophenyl)thioanisole

phenol

Downstream raw materials:

1-(4-(methylsulfonyl)phenoxy]benzene

(+/-)-Methyl-(4-phenoxy-phenyl)-sulfoxid

3,3,3-trifluoro-2-methylamino-2-(4-phenoxy-phenylsulfanylmethyl)-propionic acid

3,3,3-trifluoro-2-methylamino-2-(4-phenoxy-phenylsulfanylmethyl)-propionic acid ethyl ester