4-phenylbut-3-yn-1-yl pivalate

Base Information

• Chemical Name: 4-phenylbut-3-yn-1-yl pivalate
• CAS No.: 1160286-67-8
• Molecular Formula: C₁₅H₁₈O₂
• Molecular Weight: 230.307
• Mol file: 1160286-67-8.mol

Synonyms:4-phenylbut-3-yn-1-yl pivalate

Chemical Property of 4-phenylbut-3-yn-1-yl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4-phenylbut-3-yn-1-yl pivalate

There total 1 articles about 4-phenylbut-3-yn-1-yl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-phenyl-but-3-yn-1-ol (10229-11-5) + pivaloyl chloride (3282-30-2) → 4-phenylbut-3-yn-1-yl pivalate (1160286-67-8)

Guidance literature:

With dmap; In dichloromethane; Inert atmosphere;

Reference yield: 72.0%

4-phenylbut-3-yn-1-yl pivalate (1160286-67-8) + N-(p-tolylsulfonyl)-2-phenylaziridine (24395-14-0) → 2-(2,4-diphenyl-1-tosyl-4,5-dihydro-1H-pyrrol-3-yl)ethyl pivalate

Guidance literature:

With silver hexafluoroantimonate; In dichloromethane; 1,2-dichloro-ethane; at 20 ℃; regioselective reaction; Inert atmosphere;

Reference yield: 59.0%

4-phenylbut-3-yn-1-yl pivalate (1160286-67-8) + (E)-1-benzylidene-3,4-dihydronaphthalen-2(1H)-one (502618-02-2) → 2-(1,3-diphenyl-1H-benzo[f]chromen-2-yl)ethyl pivalate

Guidance literature:

With copper(I) oxide; tris(acetonitrile)(η5-pentamethylcyclopentadienyl)rhodium(III) hexafluoroantimonate; copper(II) acetate monohydrate; In dichloromethane; at 100 ℃; for 36h; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.7b04042

upstream raw materials:

4-phenyl-but-3-yn-1-ol

pivaloyl chloride

Downstream raw materials:

1-phenylbut-1-ene

5-phenyl-1-pentanal