(2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate

Base Information

Chemical Name:(2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate
CAS No.:1334513-08-4
Molecular Formula:C₁₈H₂₀Cl₂NO₅P
Molecular Weight:432.24
Hs Code.:

Synonyms:(2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate

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Chemical Property of (2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate

Chemical Property:

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Technology Process of (2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate

There total 1 articles about (2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 770-12-7
O-phenyl phosphorodichloridate

: 39613-92-8,62062-56-0,62062-65-1
alanine isopropyl ester hydrochloride

: 120-83-2,40477-79-0
2,4-dichlorophenol

: 1334513-08-4
(2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate

Guidance literature:: O-phenyl phosphorodichloridate; 2,4-dichlorophenol; With triethylamine; In dichloromethane; at -78 - 0 ℃;

alanine isopropyl ester hydrochloride; In dichloromethane; at 0 ℃; for 3h;
DOI:10.1021/jo201492m

Reference yield:

: 1334513-08-4
(2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate

: 362-75-4
2',3'-isopropylidene adenosine

: 1334513-09-5
(S)-isopropyl 2-(((S)-(((3aR,4R,6R,6aR)-6-(6-amino-0H-purin-9-yl)-2,2-dimethyltetrahydrofuro-[3,4-d]dioxol-4-yl)methoxy)(phenoxy)phosphoryl)amino)propionoate

Guidance literature:: 2',3'-isopropylidene adenosine; With tert-butylmagnesium chloride; In tetrahydrofuran; at 25 ℃; for 0.55h;

(2S)-isopropyl 2-(((2,4-dichlorophenoxy)(phenoxy)phosphoryl)amino)propanoate; In tetrahydrofuran; at 25 ℃;
DOI:10.1021/jo201492m