4-BUTYL PYRIDINE

Base Information

• Chemical Name: 4-BUTYL PYRIDINE
• CAS No.: 5335-75-1
• Molecular Formula: C9H13N
• Molecular Weight: 135.209
• Hs Code.: 2933399090
• Mol file: 5335-75-1.mol

Synonyms:1-(4-Pyridyl)butane;4-(n-Butyl)pyridine;4-Butylpyridine;NSC 970;

Chemical Property of 4-BUTYL PYRIDINE

Chemical Property:

• Vapor Pressure: 0.331mmHg at 25°C
• Melting Point: 31.33°C (estimate)
• Refractive Index: 1.493
• Boiling Point: 207.001 °C at 760 mmHg
• Flash Point: 81.671 °C
• PSA: 12.89000
• Density: 0.911g/cm³
• LogP: 2.42420
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

4-Butylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BUTYL PYRIDINE

There total 9 articles about 4-BUTYL PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-vinylpyridine (100-43-6,329041-72-7) + acetaldehyde hydrazone (5799-73-5) → 4-butylpyridine (5335-75-1)

Guidance literature:

With [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; 1,2-bis(dimethylphosphanyl)ethane; lithium tert-butoxide; In tetrahydrofuran; at 80 ℃; for 12h; regioselective reaction; Inert atmosphere;

DOI:10.1039/d0sc06586b

Reference yield: 60.0%

4-Butyl-4H-pyridine-1-carboxylic acid phenyl ester (86801-34-5) → 4-butylpyridine (5335-75-1) + methyl phenyl carbonate (13509-27-8)

Guidance literature:

With sodium methylate; In methanol; at 18 ℃; anodic oxidation (graphite-rod electrodes), 6 F/mol passed through the solution;

Reference yield: 5.0%

4-vinylpyridine (100-43-6,329041-72-7) + ethyl iodide (75-03-6) → 4-butylpyridine (5335-75-1)

Guidance literature:

With water; zinc; In acetonitrile; regioselective reaction; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2009.06.073

upstream raw materials:

pyridine

n-butylmercuric chloride

butyl magnesium bromide

n-butyl magnesium bromide

Downstream raw materials:

4-butylpiperidine hydrochloride

4-n-Butyl-pyridin-N-oxid

4-aminomethyl-N-[1-(4-butyl-pyridin-2-yl)-2-cyclohexyl-ethyl]-benzamide

5-Amino-pentanoic acid [(S)-1-(4-butyl-pyridin-2-yl)-2-cyclohexyl-ethyl]-amide