trans-3-Chloro-4'-methoxyacrylophenone

Base Information

• Chemical Name: trans-3-Chloro-4'-methoxyacrylophenone
• CAS No.: 15724-87-5
• Molecular Formula: C10H9 Cl O2
• Molecular Weight: 196.63
• Hs Code.: 2914700090
• Nikkaji Number: J73.344J
• Wikidata: Q76325410
• Mol file: 15724-87-5.mol

Synonyms:15724-87-5;trans-3-Chloro-4'-methoxyacrylophenone;(E)-3-chloro-1-(4-methoxyphenyl)prop-2-en-1-one;3-Chloro-1-(4-methoxyphenyl)prop-2-en-1-one;ACRYLOPHENONE, 3-CHLORO-4'-METHOXY-, (E)-;(alphaE)-beta-Chloro-4'-methoxyacrylophenone;(alphaE)-beta-Chloro-4/'-methoxyacrylophenone;p-anisyl-beta-chlorovinylketone;SCHEMBL9224403;(E)-beta-Chloro-4'-methoxyacrylophenone;trans-3-Chloro-4/'-methoxyacrylophenone;LS-14786

Chemical Property of trans-3-Chloro-4'-methoxyacrylophenone

Chemical Property:

• Vapor Pressure: 0.00179mmHg at 25°C
• Boiling Point: 292.9°C at 760 mmHg
• Flash Point: 124.5°C
• PSA: 26.30000
• Density: 1.181g/cm³
• LogP: 2.63040
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 196.0291072
• Heavy Atom Count: 13
• Complexity: 193

Purity/Quality:

3-Chloro-1-(4-methoxyphenyl)prop-2-en-1-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)C=CCl
• Isomeric SMILES: COC1=CC=C(C=C1)C(=O)/C=C/Cl

Technology Process of trans-3-Chloro-4'-methoxyacrylophenone

There total 6 articles about trans-3-Chloro-4'-methoxyacrylophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

chloroethylene (75-01-4,9002-86-2) + 4-methoxy-benzoyl chloride (100-07-2) → p-methoxyphenyl β-chlorovinyl ketone (15724-87-5)

Guidance literature:

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) + formic acid ethyl ester (109-94-4) → p-methoxyphenyl β-chlorovinyl ketone (15724-87-5)

Guidance literature:

With thionyl chloride; sodium methylate; In water; toluene; benzene;

Reference yield:

1-(4-methoxyphenyl)-2-propyn-1-one (16469-68-4) → p-methoxyphenyl β-chlorovinyl ketone (15724-87-5)

Guidance literature:

With hydrogenchloride; iron(II) sulfate; In acetic acid; at 35 ℃; for 5h;

DOI:10.1016/S0040-4039(00)00702-4

upstream raw materials:

3,3-dichloro-1-(4-methoxy-phenyl)-propan-1-one

1-(4-methoxyphenyl)-2-propyn-1-one

chloroethylene

4-methoxy-benzoyl chloride

Downstream raw materials:

trans-N-Methyl-N,N-bis-<2-chlor-aethyl>-N-<2-(4-methoxy-benzoyl)-vinyl>-ammoniumchlorid

(E)-1-Chloro-3-(4-methoxy-phenyl)-pent-1-en-4-yn-3-ol

(2E,4Z)-1,5-Bis-(4-methoxy-phenyl)-hepta-2,4-dien-6-yn-1-one

3-(p-Methoxyphenyl)-2-penten-4-ynal

Refernces

• 1、 Conde, Jose Juan,Martucci, Michael,Olsen, Mark. "A novel method for the synthesis of aromatic E-β-chlorovinylketones". . p. 4709 - 4711. Retrieved 2007/10/03.