Etofylline

Base Information

Chemical Name:Etofylline
CAS No.:519-37-9
Molecular Formula:C9H12N4O3
Molecular Weight:224.219
Hs Code.:2939590000
European Community (EC) Number:208-269-8
NSC Number:113373
UNII:L164909TBI
DSSTox Substance ID:DTXSID5023031
Nikkaji Number:J6.593E
Wikidata:Q3733837
NCI Thesaurus Code:C80611
Metabolomics Workbench ID:143455
ChEMBL ID:CHEMBL699
Mol file:519-37-9.mol

Synonyms:7-(2-hydroxyethyl)theophylline;aethophyllinum;beta-hydroxyethyltheophylline;etofylline;etophyllin;etophylline;oxyethyltheophylline;Oxyphylline;Soluphylline

Suppliers and Price of Etofylline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Etofylline
1g
$ 403.00

TRC
Etofylline
1g
$ 55.00

TCI Chemical
7-(2-Hydroxyethyl)theophylline >98.0%(HPLC)(N)
25g
$ 80.00

TCI Chemical
7-(2-Hydroxyethyl)theophylline >98.0%(HPLC)(N)
500g
$ 597.00

Sigma-Aldrich
Theophylline Related Compound F Pharmaceutical Secondary Standard; Certified Reference Material
100MG
$ 379.00

Sigma-Aldrich
Theophylline Related Compound F Pharmaceutical Secondary Standard; Certified Reference Material
100MG
$ 379.00

Sigma-Aldrich
Theophylline Related Compound F United States Pharmacopeia (USP) Reference Standard
25mg
$ 1260.00

Sigma-Aldrich
Etofylline European Pharmacopoeia (EP) Reference Standard
e2500000
$ 190.00

Sigma-Aldrich
7-(β-Hydroxyethyl)theophylline solid
25g
$ 86.10

Matrix Scientific
7-(2-Hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione 97%
1g
$ 47.00

Total 53 raw suppliers

Chemical Property of Etofylline

Chemical Property:

Vapor Pressure:1.23E-10mmHg at 25°C
Melting Point:163 °C
Refractive Index:1.683
Boiling Point:495.5 °C at 760 mmHg
PKA:14.48±0.10(Predicted)
Flash Point:253.5 °C
PSA：82.05000
Density:1.51 g/cm³
LogP:-1.57400
Storage Temp.:Refrigerator
Solubility.:H2O: Solutions may be stored for several days at 4°C.solu
Water Solubility.:2.991g/L(temperature not stated)
XLogP3:-1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:224.09094026
Heavy Atom Count:16
Complexity:322

Purity/Quality:

99%, ^*data from raw suppliers

Etofylline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xn,Xi
Statements: 22-36/37/38
Safety Statements: 36-36/37-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCO
Uses An inhibitor of 3’,5’-Cyclic Nucleotide Phosphodiesterase. Therapeutically, 7-(2-HYDROXYETHYL)THEOPHYLLINE has diuretic, muscle relaxant, bronchial dilation and CNS stimulant activities. Useful synthetic intermediate in the preparation of 7-substituted xanthines. Cardiac analeptic;Phosphodiesterase inhibitor
Therapeutic Function Antihyperlipidemic

Technology Process of Etofylline

There total 8 articles about Etofylline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%