METHYL 3-METHOXY-2-NITROBENZOATE

Base Information

• Chemical Name: METHYL 3-METHOXY-2-NITROBENZOATE
• CAS No.: 5307-17-5
• Molecular Formula: C9H9 N O5
• Molecular Weight: 211.174
• Hs Code.: 2918990090
• Mol file: 5307-17-5.mol

Synonyms:m-Anisicacid, 2-nitro-, methyl ester (6CI,7CI,8CI); Methyl 2-nitro-3-methoxybenzoate;Methyl 3-methoxy-2-nitrobenzoate

Chemical Property of METHYL 3-METHOXY-2-NITROBENZOATE

Chemical Property:

• Vapor Pressure: 0.00023mmHg at 25°C
• Melting Point: 142-144°C
• Boiling Point: 325.4°Cat760mmHg
• Flash Point: 151.5°C
• PSA: 81.35000
• Density: 1.294g/cm³
• LogP: 1.91320
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water.

Purity/Quality:

98% ^*data from raw suppliers

Methyl 3-Methoxy-2-nitrobenzoate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl 3-methoxy-2-nitrobenzoate is used as Pharmaceutical intermediates.

Technology Process of METHYL 3-METHOXY-2-NITROBENZOATE

There total 11 articles about METHYL 3-METHOXY-2-NITROBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-methoxy-2-nitrobenzoic acid (4920-80-3) + methyl iodide (74-88-4) → methyl 3-methoxy-2-nitrobenzoate (5307-17-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield: 86.0%

3-hydroxy-2-nitrobenzoic acid (602-00-6) + methyl iodide (74-88-4) → methyl 3-methoxy-2-nitrobenzoate (5307-17-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield: 60.0%

methyl 3-methoxybenzoate (5368-81-0) → methyl 3-methoxy-2-nitrobenzoate (5307-17-5)

Guidance literature:

With nitric acid; In water; at 20 ℃;

upstream raw materials:

methanol

2-nitro-3-methoxybenzoyl chloride

methyl 3-methoxybenzoate

3-methoxy-2-nitrobenzoic acid

Downstream raw materials:

methyl 2-amino-3-methoxybenzoate

2-Chloro-3-methoxybenzoic acid methyl ester

2-Chloro-3-hydroxy benzoic acid

3-Benzyloxy-2-chloro-benzoyl chloride