2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol

Base Information

• Chemical Name: 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol
• CAS No.: 125274-14-8
• Molecular Formula: C₃₉H₅₆O₁₁
• Molecular Weight: 700.867
• Mol file: 125274-14-8.mol

Synonyms:2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol

Chemical Property of 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol

Chemical Property:

Purity/Quality:

>98.00% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol

There total 9 articles about 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(methylsulfonyl)-15-(triphenylcarbinyl)-3,6,9,12,15-pentaoxapentadecane + Pentaethylene glycol (4792-15-8) → 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol (125274-14-8)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 48h; Heating;

DOI:10.1021/ja027332j

Reference yield: 55.0%

hexa(ethyleneglycol) ditosylate (42749-27-9) + 2-(2-trityloxyethoxy)ethanol (105589-77-3) → 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol (125274-14-8)

Guidance literature:

2-(2-trityloxyethoxy)ethanol; With sodium hydride; In tetrahydrofuran; at 50 ℃; for 0.166667h;

hexa(ethyleneglycol) ditosylate; In tetrahydrofuran; at 80 ℃; for 5h; Further stages.;

DOI:10.1021/ja026895s

Reference yield:

pentaethylene glycol (2615-15-8) → 2-{2-[2-(2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol (125274-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 42 percent / pyridine / 74 h / -20 °C

2.1: NaH / tetrahydrofuran / 0.17 h / 50 °C

2.2: 55 percent / tetrahydrofuran / 5 h / 80 °C

With pyridine; sodium hydride; In tetrahydrofuran;

DOI:10.1021/ja026895s

upstream raw materials:

hexa(ethyleneglycol) ditosylate

2-(2-trityloxyethoxy)ethanol

Pentaethylene glycol

pentaethylene glycol

Downstream raw materials:

2-(2-(2-(2-(2-(2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethanamine

1-azide-31,31,31-triphenyl-3,6,9,12,15,18,21,24,27,30-decaoxahentriacontanol

29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol

decaethylene glycol