1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene

Base Information

Chemical Name:1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene
CAS No.:1245566-04-4
Molecular Formula:C₂₀H₁₇ClN₂O₂
Molecular Weight:352.82
Hs Code.:

Synonyms:1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene

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Technology Process of 1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene

There total 1 articles about 1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 623-03-0
4-Cyanochlorobenzene

: 75632-83-6
3-methyl-5-[(trimethylsilyl)methyl]isoxazole

: 123-11-5
4-methoxy-benzaldehyde

: 1245566-04-4
1-(4-methoxyphenyl)-3-(4-chlorophenyl)-4-(3-methylisoxazol-5-yl)-2-aza-1,3-butadiene

Guidance literature:: 3-methyl-5-[(trimethylsilyl)methyl]isoxazole; With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 1h; Inert atmosphere;

4-Cyanochlorobenzene; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 2h; Inert atmosphere;

4-methoxy-benzaldehyde; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/ejoc.201000241