Methyl 4-chloro-3-(chlorosulfonyl)benzoate

Base Information

Chemical Name:Methyl 4-chloro-3-(chlorosulfonyl)benzoate
CAS No.:1000933-19-6
Molecular Formula:C₈H₆Cl₂O₄S
Molecular Weight:269.105
Hs Code.:2904990090
European Community (EC) Number:848-280-0
Mol file:1000933-19-6.mol

Synonyms:methyl 4-chloro-3-(chlorosulfonyl)benzoate;1000933-19-6;methyl 4-chloro-3-chlorosulfonylbenzoate;methyl 4-chloro-3-chlorosulfonyl-benzoate;SCHEMBL1495720;SXAYTEZGGGOESJ-UHFFFAOYSA-N;MFCD09816501;AKOS000166359;BS-29892;methyl4-chloro-3-(chlorosulfonyl)benzoate;DB-308332;CS-0205773;EN300-31348;G22332;J-000042;methyl 4-chloro-3-(chlorosulfonyl)benzoate, AldrichCPR;Z285673148

Suppliers and Price of Methyl 4-chloro-3-(chlorosulfonyl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Apolloscientific
Methyl 4-chloro-3-(chlorosulfonyl)benzoate 96%
1g
$ 298.00

Apolloscientific
Methyl 4-chloro-3-(chlorosulfonyl)benzoate 96%
250mg
$ 117.00

Apolloscientific
Methyl 4-chloro-3-(chlorosulfonyl)benzoate 96%
5g
$ 851.00

American Custom Chemicals Corporation
METHYL 4-CHLORO-3-(CHLOROSULFONYL)BENZOATE 95.00%
1G
$ 852.55

American Custom Chemicals Corporation
METHYL 4-CHLORO-3-(CHLOROSULFONYL)BENZOATE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
METHYL 4-CHLORO-3-(CHLOROSULFONYL)BENZOATE 95.00%
2.5G
$ 1227.82

AK Scientific
Methyl4-chloro-3-(chlorosulfonyl)benzoate
2.5g
$ 892.00

AK Scientific
Methyl4-chloro-3-(chlorosulfonyl)benzoate
1g
$ 503.00

Total 5 raw suppliers

Chemical Property of Methyl 4-chloro-3-(chlorosulfonyl)benzoate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:267.9363852
Heavy Atom Count:15
Complexity:335

Purity/Quality:

99% ^*data from raw suppliers

Methyl 4-chloro-3-(chlorosulfonyl)benzoate 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(C=C1)Cl)S(=O)(=O)Cl

Technology Process of Methyl 4-chloro-3-(chlorosulfonyl)benzoate

There total 3 articles about Methyl 4-chloro-3-(chlorosulfonyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 67-56-1
methanol

: 2494-79-3
4-chloro-3-(chlorosulfonyl)benzoic acid

: 1000933-19-6
methyl 4-chloro-3-(chlorosulfonyl)benzoate

Guidance literature:: 4-chloro-3-(chlorosulfonyl)benzoic acid; With thionyl chloride; at 20 ℃; for 16h; Inert atmosphere;

methanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b00293

Reference yield: 89.0%

: 67-56-1
methanol

: 62574-66-7
3-chlorosulfonyl-4-chlorobenzoyl chloride

: 1000933-19-6
methyl 4-chloro-3-(chlorosulfonyl)benzoate

Guidance literature:: With triethylamine; In acetonitrile; pH=7 - 8;
DOI:10.1007/s11172-016-1518-5

Reference yield:

: 74-11-3
para-chlorobenzoic acid

: 1000933-19-6
methyl 4-chloro-3-(chlorosulfonyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: chlorosulfonic acid / 0 - 130 °C

1.2: 0.17 h / 0 °C

2.1: thionyl chloride / 0 °C / Reflux

With chlorosulfonic acid; thionyl chloride;