2,2-Dichloro-1,1,1-trifluoroethane

Base Information

• Chemical Name: 2,2-Dichloro-1,1,1-trifluoroethane
• CAS No.: 306-83-2
• Molecular Formula: C2HCl2F3
• Molecular Weight: 152.931
• Hs Code.: 2903399090
• European Community (EC) Number: 206-190-3
• ICSC Number: 1343
• UN Number: 1078
• UNII: 6S7C791U3V
• DSSTox Substance ID: DTXSID7020712
• Nikkaji Number: J11.841I
• Wikipedia: 2,2-Dichloro-1,1,1-trifluoroethane
• Wikidata: Q1869625
• Mol file: 306-83-2.mol

Synonyms:1,1-dichloro-2,2,2-trifluoroethane;2,2-DCTFE;2,2-dichloro-1,1,1-trifluoroethane;FC-123;Freon 123;Freon-123;HCFC 123;HCFC-123

Chemical Property of 2,2-Dichloro-1,1,1-trifluoroethane

Chemical Property:

• Appearance/Colour: Colorless nonflammable gas
• Vapor Pressure: 633mmHg at 25°C
• Melting Point: -107 °C
• Refractive Index: 1.344
• Boiling Point: 30.112 °C at 760 mmHg
• Flash Point: -34.591 °C
• PSA: 0.00000
• Density: 1.513 g/cm³
• LogP: 2.35240
• Storage Temp.: 2-8°C
• Water Solubility.: 2.1g/L at 25℃
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 151.9407399
• Heavy Atom Count: 7
• Complexity: 56.4

Purity/Quality:

99.9% ^*data from raw suppliers

2,2-Dichloro-1,1,1-trifluoroethane 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,Xi
• Hazard Codes: T,Xi,N
• Statements: 23/24/25-39-39/23/24/25-59
• Safety Statements: 36/37-45-59

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: C(C(F)(F)F)(Cl)Cl
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. This may result in narcosis and cardiac disorders.
• Effects of Long Term Exposure: The substance may have effects on the liver.
• Uses: HCFC 123 is an interim replacement for the CFCs and is scheduled for a production phase-out during the 2020s. Its main application is as a substitute for CFC 11 in centrifugal chillers used for air conditioning of large buildings. It is also used in smaller air-conditioning units, and may have applications in foam blowing, and firefighting and as a chemical intermediate.

Technology Process of 2,2-Dichloro-1,1,1-trifluoroethane

There total 62 articles about 2,2-Dichloro-1,1,1-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.8%

1,1,2,2-tetrachloroethylene (127-18-4) → 1,1,1-trifluoro-2,2-dichloroethane (306-83-2) + 1,1,2-trichloro-2,2-difluoroethane (354-21-2) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

With hydrogen fluoride; antimony(III) fluoride; antimony pentafluoride; at 129 - 143 ℃; for 4.1h; under 17626.8 - 19502 Torr;

Reference yield: 3.1%

1,1,2,2-tetrachloroethylene (127-18-4) → 1,1,1-trifluoro-2,2-dichloroethane (306-83-2) + 1,1,2-trichloro-2,2-difluoroethane (354-21-2) + freon-121 (354-14-3) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

With hydrogen fluoride; antimony(III) fluoride; antimony pentafluoride; at 125 - 139 ℃; for 3.7h; under 16351.6 - 18376.8 Torr;

Reference yield:

1,1,2-Trichloro-1,2,2-trifluoroethane (76-13-1) → methane (34557-54-5,27936-85-2) + trifluoromethan (75-46-7) + chloroform (67-66-3,8013-54-5) + 2,2,2-trifluoroethanol (420-46-2) + 1,1,1-trifluoro-2-chloroethane (75-88-7) + 1,1,1-trifluoro-2,2-dichloroethane (306-83-2)

Guidance literature:

With hydrogen; palladium; zinc(II) oxide; at 399.9 ℃; Product distribution; var. of catalyst, Pd/Zn ratio, temp.;

DOI:10.1039/c39940002385

upstream raw materials:

2,2,2-trifluoroethanol

1,1,1-trifluoro-2-chloroethane

1,1,2-trichloro-2,2-difluoroethane

F₁₂₁a

Downstream raw materials:

1,1,1-trifluoro-2-chloroethane

1-Chloro-2,2-difluoroethene

1,1,1-trifluoro-2-bromo-2-chloroethane

trifluoroacetic acid

Refernces

• 1、 Haszeldine,Nyman. "-". . p. 420. Retrieved 1959.
• 2、 Hu, Chang-Ming,Tu, Ming-Hu. "Reduction of polyhalofluoroalkanes with formate to hydrogen-bearing alternatives initiated by carbon dioxide anionic radical". . p. 105 - 108. Retrieved 1991.
• 3、 Kemnitz, Erhard,Zhu,Adamczyk. "Enhanced Lewis acidity by aliovalent cation doping in metal fluorides". . p. 163 - 170. Retrieved 2002.
• 4、 -. "Preparation method of trifluoroacetic acid". Paragraph 0025; 0028; 0031; 0034; 0037. . Retrieved 2019/01/16.
• 5、 -. "Method for combined production of 1,1,2-trifluorotrichloroethane and 1,1,1-trifluorodichloroethane". Paragraph 0036; 0037. . Retrieved 2017/01/12.