N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid

Base Information

• Chemical Name: N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid
• CAS No.: 696604-98-5
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.314
• Mol file: 696604-98-5.mol

Synonyms:N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid

Chemical Property of N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid

There total 3 articles about N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methanol (67-56-1) + (2-nitro-phenyl)-carbamic acid tert-butyl ester (54614-93-6) → N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid (696604-98-5)

Guidance literature:

With formaldehyd; formic acid; palladium 10% on activated carbon; hydrogen; for 3h;

DOI:10.3390/molecules19022571

Reference yield: 75.0%

N,N-dimethyl-1,2-phenylenediamine (2836-03-5) + di-tert-butyl dicarbonate (24424-99-5) → N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid (696604-98-5)

Guidance literature:

N,N-dimethyl-1,2-phenylenediamine; With bis(tri-ortho-tolylphosphine)palladium⁽⁰⁾; (R)-(-)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyl-di-tert-butylphosphine; ammonia; sodium t-butanolate; In 1,4-dioxane; at 100 ℃; for 12h; Inert atmosphere;

di-tert-butyl dicarbonate; With triethylamine; In 1,4-dioxane; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja903049z

Reference yield: 70.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + tert–butyl (2–aminophenyl)carbamate (146651-75-4) → N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid (696604-98-5)

Guidance literature:

formaldehyd; tert–butyl (2–aminophenyl)carbamate; In methanol; at 20 ℃; for 2h;

With Decaborane; In methanol; at 20 ℃; for 2h; Further stages.;

DOI:10.1039/b313996d

upstream raw materials:

formaldehyd

tert–butyl (2–aminophenyl)carbamate

N,N-dimethyl-1,2-phenylenediamine

di-tert-butyl dicarbonate

Downstream raw materials:

N,N-dimethyl-1,2-phenylenediamine

2-amino-N-[2-(N,N-dimethylamino)phenyl]ethanamide

N-[2-(N,N-dimethylamino)phenyl]-2-[(phenylmethoxy)carbonylamino]ethanamide