ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Base Information

Chemical Name:ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate
CAS No.:1246609-98-2
Molecular Formula:C₂₅H₃₃N₃O₄
Molecular Weight:439.555
Hs Code.:

Synonyms:ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Suppliers and Price of ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

There total 3 articles about ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 3-amino-3-anilinoacrylate

: 1246609-97-1
tert-butyl (1s,4s)-4-propioloylcyclohexylcarbamate

: 1246609-98-2
ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Guidance literature:: In ethanol; for 24h; Reflux;

Reference yield:

: 53292-90-3
cis-4-tert-butoxycarbonylaminocyclohexane-1-ylcarboxylic acid

: 1246609-98-2
ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Guidance literature:: Multi-step reaction with 3 steps

1.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / tetrahydrofuran / 48 h / 20 °C

2.1: ethyl acetate; tetrahydrofuran / 4 h / 0 °C

2.2: Cooling with ice

3.1: ethanol / 24 h / Reflux

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In tetrahydrofuran; ethanol; ethyl acetate; 3.1: Bohlman-Rahtz Reaction;

Reference yield:

: 304873-79-8
tert-butyl ((1s,4s)-4-(methoxy(methyl)carbamoyl)cyclohexyl)carbamate

: 1246609-98-2
ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethyl acetate; tetrahydrofuran / 4 h / 0 °C

1.2: Cooling with ice

2.1: ethanol / 24 h / Reflux

In tetrahydrofuran; ethanol; ethyl acetate; 2.1: Bohlman-Rahtz Reaction;