1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene

Base Information

• Chemical Name: 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene
• CAS No.: 168482-52-8
• Molecular Formula: C₁₄H₃₀OSiSn
• Molecular Weight: 361.187
• Mol file: 168482-52-8.mol

Synonyms:1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene

Chemical Property of 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene

There total 1 articles about 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(trimethylstannyl)lithium (17946-71-3) + chloro-trimethyl-silane (75-77-4) + 2-ethylidenecyclohexan-1-one (1122-25-4) → 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene (168482-52-8)

Guidance literature:

With sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; addn. of soln. of enone to soln. Me3SnLi, addn. of triethylamine and then trimethysilyl chloride (room temp.), stirring (10 min), quenching (sat. aq. NaHCO3);

DOI:10.1246/bcsj.68.289

Reference yield: 69.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene (168482-52-8) → 2-hydroxymethyl-2-(1-trimethylstannylethyl)-1-cyclohexane

Guidance literature:

yttrium(III) trifluoromethanesulfonate; In tetrahydrofuran; water; addn. of soln. of Sn compound in THF to soln. of formalin (35 %) with Y(OTf)3 (room temp.), stirring (55 h); extn. into ether, column chromy.;

DOI:10.1246/bcsj.68.289

Reference yield: 40.0%

1,1-dimethoxyethane (534-15-6) + 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene (168482-52-8) → 2-(1-methoxyethyl)-2-(1-trimethylstannylethyl)-1-cyclohexanone

Guidance literature:

With sodium hydrogencarbonate; titanium tetrachloride; In dichloromethane; addn. of TiCl4 to mixt. of Sn compound and acetaldehyde dimethyl acetal in CH2Cl2 (-78°C), stirring (30 min), treating with NaHCO3; extn. into CH2Cl2; mixt. of diastereomers not sepd. (ratio 83 : 17);

DOI:10.1246/bcsj.68.289

upstream raw materials:

(trimethylstannyl)lithium

chloro-trimethyl-silane

2-ethylidenecyclohexan-1-one