Methyl N-(3-chlorophenyl)carbamate

Base Information

• Chemical Name: Methyl N-(3-chlorophenyl)carbamate
• CAS No.: 2150-88-1
• Molecular Formula: C8H8 Cl N O2
• Molecular Weight: 185.61
• European Community (EC) Number: 633-666-1
• DSSTox Substance ID: DTXSID40175842
• Nikkaji Number: J540.716H
• Wikidata: Q83046171
• Mol file: 2150-88-1.mol

Synonyms:METHYL N-(3-CHLOROPHENYL)CARBAMATE;2150-88-1;Methyl (3-chlorophenyl)carbamate;Carbamic acid, 3-chlorophenyl-, methyl ester;Enamine_005868;Cambridge id 5103637;methyl 3-chlorophenylcarbamate;SCHEMBL1188370;DTXSID40175842;SEPMCAVKHUPSMA-UHFFFAOYSA-N;HMS1410K16;methyl-N-(3-chlorophenyl)carbamate;AKOS001022202;3-Chlorophenylcarbamic acid methyl ester;IDI1_008103;(3-Chloro-phenyl)-carbamic acid methyl ester;F81747;Z56754690;F3035-0947

Chemical Property of Methyl N-(3-chlorophenyl)carbamate

Chemical Property:

• Vapor Pressure: 0.121mmHg at 25°C
• Boiling Point: 219.2°Cat760mmHg
• Flash Point: 86.3°C
• Density: 1.317g/cm³
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 185.0243562
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)NC1=CC(=CC=C1)Cl

Technology Process of Methyl N-(3-chlorophenyl)carbamate

There total 13 articles about Methyl N-(3-chlorophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + carbon monoxide (201230-82-2) + 3-chloro-aniline (108-42-9) → methyl-N-(3-chlorophenyl)carbamate (2150-88-1)

Guidance literature:

With copper diacetate; palladium diacetate; potassium iodide; In dimethyl sulfoxide; at 120 ℃; under 760.051 Torr;

DOI:10.1002/adsc.201100545

Reference yield: 95.0%

methyl chloroformate (79-22-1) + 3-chloro-aniline (108-42-9) → methyl-N-(3-chlorophenyl)carbamate (2150-88-1)

Guidance literature:

In toluene; for 2h; Heating;

DOI:10.1002/(SICI)1096-9063(199911)55:11<1116::AID-PS65>3.0.CO;2-Y

Reference yield: 92.0%

methanol (67-56-1) + 3-chlorobenzamide (618-48-4) → methyl-N-(3-chlorophenyl)carbamate (2150-88-1)

Guidance literature:

With sodium bromide; In acetonitrile; at 50 ℃; for 6h; Electrochemical reaction; Green chemistry;

DOI:10.1039/c8ob01059e

upstream raw materials:

methyl chloroformate

3-chloro-aniline

methanol

m-chlorophenyl isocyanate

Downstream raw materials:

(3-chloro-2,6-dinitro-phenyl)-carbamic acid methyl ester

(5-chloro-2,4-dinitro-phenyl)-carbamic acid methyl ester

Chloromethyl-(3-chloro-phenyl)-carbamic acid methyl ester

3-chloro-aniline