N-Acetyl-L-tryptophan

Base Information

Chemical Name:N-Acetyl-L-tryptophan
CAS No.:1218-34-4
Molecular Formula:C13H14N2O3
Molecular Weight:246.266
Hs Code.:29339900
European Community (EC) Number:214-935-9
UNII:U9264T8OAE
DSSTox Substance ID:DTXSID10883669
Nikkaji Number:J61.737G
Wikidata:Q27144794
NCI Thesaurus Code:C77305
RXCUI:1368212
Metabolomics Workbench ID:87144
ChEMBL ID:CHEMBL54170
Mol file:1218-34-4.mol

Synonyms:acetyltryptophan;N-acetyl-D-tryptophan;N-acetyltryptophan;N-acetyltryptophanate sodium

Suppliers and Price of N-Acetyl-L-tryptophan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Acetyl-L-Tryptophan
10g
$ 90.00

TCI Chemical
N-Acetyl-L-tryptophan >98.0%(HPLC)
25g
$ 71.00

TCI Chemical
N-Acetyl-L-tryptophan >98.0%(HPLC)
1g
$ 15.00

Sigma-Aldrich
Tryptophan Related Compound B United States Pharmacopeia (USP) Reference Standard
25mg
$ 1230.00

Sigma-Aldrich
N-Acetyltryptophan European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
N-Acetyltryptophan European Pharmacopoeia (EP) Reference Standard
a0208000
$ 190.00

Sigma-Aldrich
N-Acetyl-L-tryptophan Pharmaceutical Secondary Standard; Certified Reference Material
500mg
$ 102.00

Sigma-Aldrich
N-Acetyl-L-tryptophan
10g
$ 60.40

Sigma-Aldrich
N-Acetyl-L-tryptophan
25g
$ 119.00

Crysdot
Ac-Trp-OH 98%
100g
$ 116.00

Total 159 raw suppliers

Chemical Property of N-Acetyl-L-tryptophan

Chemical Property:

Appearance/Colour:solid
Vapor Pressure:1.32E-14mmHg at 25°C
Melting Point:186 °C
Refractive Index:1.645
Boiling Point:586.6 °C at 760 mmHg
PKA:3.65±0.10(Predicted)
Flash Point:308.6 °C
PSA：82.19000
Density:1.33g/cm3
LogP:1.69060
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:246.10044231
Heavy Atom Count:18
Complexity:332

Purity/Quality:

98.0% min ^*data from raw suppliers

N-Acetyl-L-Tryptophan ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O
Isomeric SMILES:CC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O
Uses N-Acetyl-L-Tryptophan, is a derivative of L-Tryptophan (T947210), that can be used as competitive inhibitor to identify and characterize tryptophanases. It can also be used as an NK1 tachykinin receptor antagonist, that may help to develop a novel therapeutic intervention for the treatment of reperfusion injury in acute ischemic stroke.

Technology Process of N-Acetyl-L-tryptophan

There total 50 articles about N-Acetyl-L-tryptophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 2824-57-9,16108-06-8,36060-94-3
N-acetyltryptophan methyl ester

: 1218-34-4
N-AcTrp

: 2824-57-9,16108-06-8,36060-94-3
AcTrpOMe

Guidance literature:: With sodium hydroxide; phosphate buffer; pronase EC 3.4.24.4; In tetrahydrofuran; Ambient temperature;

Reference yield: 80.0%

: 75-36-5
acetyl chloride

: 73-22-3,27732-43-0,80206-30-0,27813-82-7
L-Tryptophan

: 1218-34-4
N-AcTrp

Guidance literature:: With sodium hydroxide; In acetone; at 20 ℃; pH=> 10;
DOI:10.1016/j.bmc.2014.08.035

Reference yield: 76.0%

: 507-09-5
tiolacetic acid

: 73-22-3,27732-43-0,80206-30-0,27813-82-7
L-Tryptophan

: 1218-34-4
N-AcTrp

Guidance literature:: tiolacetic acid; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

L-Tryptophan; With 2,4-Dinitrofluorobenzene; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
DOI:10.1002/anie.200805782