4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate

Base Information

• Chemical Name: 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate
• CAS No.: 153886-95-4
• Molecular Formula: C₁₅H₂₇O₅PSi
• Molecular Weight: 346.436
• Mol file: 153886-95-4.mol

Synonyms:4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate

Chemical Property of 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate

There total 3 articles about 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-hydroxyphenyl)methanol (623-05-2) → 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate (153886-95-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / 1H-imidazole / dimethylformamide / 48 h / Ambient temperature

With 1H-imidazole; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19930760706

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate (153886-95-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / 1H-imidazole / dimethylformamide / 48 h / Ambient temperature

With 1H-imidazole; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19930760706

Reference yield:

1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene (117635-46-8) + Dimethyl phosphite (868-85-9) → 4-(<(tert-butyl)dimethylsilyloxy>methyl)phenyl dimethyl phosphate (153886-95-4)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1002/hlca.19930760706

upstream raw materials:

1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene

Dimethyl phosphite

(4-hydroxyphenyl)methanol

tert-butyldimethylsilyl chloride

Downstream raw materials:

4'-O-benzyl-N²-<(tert-butyloxy)carbonyl>-3-(dimethoxyphosphoryl)-L-tyrosine

dimethyl 2-(benzyloxy)-5-(hydroxymethyl)phenylphosphonate

dimethyl 2-(benzyloxy)-5-formylphenylphosphonate

dimethyl 2-hydroxy-5-(<(tert-butyl)dimethylsilyloxy>methyl)phenylphosphonate