2,2,3,3,4,4,5,5-Octafluoro-1-pentanol

Base Information

• Chemical Name: 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol
• CAS No.: 355-80-6
• Deprecated CAS: 855832-03-0
• Molecular Formula: C5H4F8O
• Molecular Weight: 232.073
• Hs Code.: 29055910
• European Community (EC) Number: 206-593-4
• NSC Number: 114
• UNII: D05K8EJX15
• DSSTox Substance ID: DTXSID0059879
• Nikkaji Number: J10.710G
• Wikidata: Q27275927
• ChEMBL ID: CHEMBL4513664
• Mol file: 355-80-6.mol

Synonyms:2,2,3,3,4,4,5,5-Octafluoro-1-pentanol;355-80-6;2,2,3,3,4,4,5,5-Octafluoropentan-1-ol;1H,1H,5H-Octafluoro-1-pentanol;1-PENTANOL, 2,2,3,3,4,4,5,5-OCTAFLUORO-;1,1,5-Trihydrooctafluoropentyl alcohol;1,1,5-Trihydrooctafluoropentan-1-ol;2,2,3,3,4,4,5,5-Octafluoropentanol;1h,1h,5h-octafluoropentan-1-ol;NSC 114;1h,1h,5h-perfluoropentanol;1h,1h,5h-octafluoropentanol;C5H4F8O;2,2,3,3,4,4,5,5-Octafluoropentyl alcohol;EINECS 206-593-4;MFCD00039631;BRN 1773494;UNII-D05K8EJX15;alpha,alpha,omega-Trihydroperfluoropentanol;AI3-23780;D05K8EJX15;NSC-114;.alpha.,.alpha.,.omega.-Trihydroperfluoropentanol;4-01-00-01648 (Beilstein Handbook Reference);NSC114;WLN: Q1XFFXFFXFFYFF;CHF2CF2CF2CF2CH2OH;H(CF2)4CH2OH;SCHEMBL21426;1H,5H-Octafluoro-1-pentanol;1,1,5-trihydroperfluoropentanol;CHEMBL4513664;DTXSID0059879;AMY6901;1,5-Trihydrooctafluoropentan-1-ol;1,5-Trihydrooctafluoropentyl alcohol;AC-660;FD2061;1,1,5-Trihydrooctafluoro-1-pentanol;AKOS000120103;2,3,3,4,4,5,5-Octafluoropentanol;1H,1H,5H-OCTAFLUORO-N-PENTANOL;AS-63089;SY048946;2,3,3,4,4,5,5-Octafluoro-1-pentanol;2,3,3,4,4,5,5-Octafluoropentyl alcohol;LS-101908;1-Pentanol,2,3,3,4,4,5,5-octafluoro-;2,2,3,3,4,4,5,5octafluoro-1-pentanol;CS-0121491;FT-0607837;O0114;EN300-19340;2,2,3,3,4,4,5,5-octafluoro-pentan-1-ol;1,1,5-TRIHYDRO-1-HYDROXYPERFLUOROPENTANE;2,2,3,3,4,4,5,5-Octafluoro-1-pentanol, 98%;Q27275927;2,2,3,3,4,4,5,5-OCTAFLUORO-1-PENTANOL [MI]

Chemical Property of 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol

Chemical Property:

• Appearance/Colour: Colorless liquid.
• Vapor Pressure: 2.52mmHg at 25°C
• Melting Point: <-50 °C
• Refractive Index: n20/D 1.318(lit.)
• Boiling Point: 140.5 °C at 760 mmHg
• PKA: 12.91±0.10(Predicted)
• Flash Point: 75.6 °C
• PSA: 20.23000
• Density: 1.519 g/cm³
• LogP: 2.14970
• Storage Temp.: 2-8°C
• Water Solubility.: insoluble
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 4
• Exact Mass: 232.01344004
• Heavy Atom Count: 14
• Complexity: 200

Purity/Quality:

99.9% ^*data from raw suppliers

2,2,3,3,4,4,5,5-Octafluoro-1-pentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,F
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: PFAS,Other Classes -> Halogenated Alcohols
• Canonical SMILES: C(C(C(C(C(F)F)(F)F)(F)F)(F)F)O
• Uses: 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol is used as a cosurfactant in the synthesis of silver and silver iodide nanocrystals. It was also used in the synthesis of Ag2S nanocrystals with a characteristic surface plasmon resonance absorption at 330nm.

Technology Process of 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol

There total 22 articles about 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

methyl 2,2,3,3,4,4,5,5-octafluoropentanoate (54822-22-9) → 2,2,3,3,4,4,5,5-octafluoropentan-1-ol (355-80-6)

Guidance literature:

methyl 2,2,3,3,4,4,5,5-octafluoropentanoate; With polyethylsiloxane; LiTi(OPr-i)4; at 100 ℃; for 24h;

With sodium hydroxide; In tetrahydrofuran; for 3h; Heating;

DOI:10.1023/B:RUJO.0000044534.92992.fc

Reference yield: 35.0%

pentakis-(2,2,3,3,4,4,5,5-octafluoro-pentyloxy)-λ5-phosphane (71879-03-3) + thiophenol (108-98-5) → 2,2,3,3,4,4,5,5-octafluoropentan-1-ol (355-80-6) + tris(2,2,3,3,4,4,5,5-octafluoropentyl) phosphite (65611-17-8) + diphenyldisulfane (882-33-7) + (2,2,3,3,4,4,5,5-Octafluoro-pentylsulfanyl)-benzene

Guidance literature:

at 200 ℃; for 7h;

Reference yield:

methanol (67-56-1) + polytetrafluoroethylene (116-14-3,82785-14-6) → 2,2,3,3-tetrafluoropropanol (76-37-9) + 2,2,3,3,4,4,5,5-octafluoropentan-1-ol (355-80-6)

Guidance literature:

With dibenzoyl peroxide; at -30 ℃; for 6h; Yields of byproduct given;

DOI:10.1016/S0022-1139(00)83928-7

upstream raw materials:

methanol

polytetrafluoroethylene

chloral hydrate

C₁₂H₁₁F₁₆O₂P

Downstream raw materials:

Glutarsaeure-bis-(1H,1H,5H-octafluor-pentylester)

di(2,2,3,3,4,4,5,5-octafluoropent-1-yl) phthalate

acrylate de trihydro-1,1,5 octafluoropentyle

2,2,3,3,4,4,5,5-octafluoropentyl methacrylate

Refernces

• 1、 Nalet'Ko,Pervova,Gorbunova,Zapevalov, A. Ya,Toporova,Saloutin. "Thermal desulfurization of (Alkoxymethyl)thiiranes". . p. 2120 - 2124. Retrieved 2015/02/02.
• 2、 Krutikova,Krutikov,Erkin. "Polyfluoroalloxy phosphonic and phosphinic acid derivatives: I. 1-Hydroxy-2,2,2-trichloroethylphosphinates". experimental part. p. 428 - 433. Retrieved 2010/08/04.