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Arginine Hydrochloride

Base Information Edit
  • Chemical Name:Arginine Hydrochloride
  • CAS No.:1119-34-2
  • Molecular Formula:C6H14N4O2.HCl
  • Molecular Weight:210.664
  • Hs Code.:29252000
  • European Community (EC) Number:214-275-1,239-674-8
  • DSSTox Substance ID:DTXSID20883650
  • Wikidata:Q27277776
  • NCI Thesaurus Code:C29606
  • RXCUI:89918
  • ChEMBL ID:CHEMBL1200381
  • Mol file:1119-34-2.mol
Arginine Hydrochloride

Synonyms:Arginine;Arginine Hydrochloride;Arginine, L Isomer;Arginine, L-Isomer;DL Arginine Acetate, Monohydrate;DL-Arginine Acetate, Monohydrate;Hydrochloride, Arginine;L Arginine;L-Arginine;L-Isomer Arginine;Monohydrate DL-Arginine Acetate

Suppliers and Price of Arginine Hydrochloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • L-Arginine Hydrochloride
  • 100g
  • $ 106.00
  • TRC
  • L-(+)-Arginine Hydrochloride
  • 50g
  • $ 80.00
  • TRC
  • L-(+)-Arginine Hydrochloride
  • 25g
  • $ 70.00
  • TCI Chemical
  • L-(+)-Arginine Hydrochloride >98.0%(HPLC)(T)
  • 500g
  • $ 96.00
  • TCI Chemical
  • L-(+)-Arginine Hydrochloride >98.0%(HPLC)(T)
  • 25g
  • $ 18.00
  • SynQuest Laboratories
  • L-Arginine hydrochloride
  • 100 g
  • $ 29.00
  • SynQuest Laboratories
  • L-Arginine hydrochloride
  • 1 kg
  • $ 144.00
  • SynQuest Laboratories
  • L-Arginine hydrochloride
  • 500 g
  • $ 80.00
  • Sigma-Aldrich
  • Arginine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • 1g
  • $ 78.20
  • Sigma-Aldrich
  • L-Arginine monohydrochloride not synthetic, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
  • 100g
  • $ 75.60
Total 286 raw suppliers
Chemical Property of Arginine Hydrochloride Edit
Chemical Property:
  • Appearance/Colour:White crystalline powder 
  • Vapor Pressure:7.7E-08mmHg at 25°C 
  • Melting Point:226-230 °C 
  • Boiling Point:409.1 °C at 760 mmHg 
  • PKA:1[at 20 ℃] 
  • Flash Point:201.2 °C 
  • PSA:125.22000 
  • Density:1.46 g/cm3 
  • LogP:1.35480 
  • Storage Temp.:2-8°C 
  • Sensitive.:Hygroscopic 
  • Solubility.:H2O: 100 mg/mL 
  • Water Solubility.:Soluble in water. Slightly soluble in hot alcohol. 
  • Hydrogen Bond Donor Count:5
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:5
  • Exact Mass:210.0883534
  • Heavy Atom Count:13
  • Complexity:176

98% *data from raw suppliers

L-Arginine Hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi,HarmfulXn 
  • Hazard Codes:Xi,Xn 
  • Statements: 37-36/38-36/37/38-20/21/22 
  • Safety Statements: 37/39-26-24/25-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

  • Chemical Classes:Biological Agents -> Amino Acids and Derivatives
  • Canonical SMILES:C(CC(C(=O)O)N)CN=C(N)N.Cl
  • Isomeric SMILES:C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
  • Recent ClinicalTrials:Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial
  • Recent EU Clinical Trials:Multicenter, open label trial to investigate the efficacy and safety of a single oral dose of 1.0 mg/kg macimorelin acetate as growth hormone stimulation test (GHST) in pediatric patients with suspected growth hormone deficiency (GHD)
  • Chemical Composition Arginine Hydrochloride, also known as l-Arginine hydrochloride, is composed of the amino acid arginine and hydrochloric acid.
  • Mechanism of Action Arginine Hydrochloride acts as an aggregation suppressor, reducing protein aggregation in solution. It interacts with protein molecules through hydrophobic and aromatic interactions, decreasing solution viscosity.
  • Uses Arginine Hydrochloride is utilized in the formulation of high-concentration protein drugs to decrease solution viscosity, particularly in antibody formulations. It has shown efficacy in reducing viscosity and stabilizing proteins. It interacts with charged and hydrophobic residues on antibodies, influencing protein-protein interactions.
  • FDA Approval The approval of arginine HCl for intravenous administration was reflected in the FDA's authorization of R-Gene 10 as a 10 gram (GM)/100 mL (100 mg/mL; 10 percent) injection for intravenous use. Additionally, arginine HCl is proposed for use in compounding single-ingredient drug products for oral use. Arginine HCl is considered suitable for compounding oral formulations for certain patients, particularly those with specific urea cycle disorders (UCDs).
Technology Process of Arginine Hydrochloride

There total 17 articles about Arginine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In 1,4-dioxane;
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