2-(N,N-dimethylamino)phenylboronic acid dimethyl ester

Base Information

• Chemical Name: 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester
• CAS No.: 313220-10-9
• Molecular Formula: C₁₀H₁₆BNO₂
• Molecular Weight: 193.054
• Mol file: 313220-10-9.mol

Synonyms:2-(N,N-dimethylamino)phenylboronic acid dimethyl ester

Chemical Property of 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester

There total 3 articles about 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

Trimethyl borate (121-43-7,63156-11-6) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester (313220-10-9)

Guidance literature:

N,N-dimethyl-aniline; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at 20 ℃; for 12h;

Trimethyl borate; In hexane; at 20 ℃; for 8h; Further stages.;

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + hydrogen (1333-74-0) + 2-(N,N-dimethylamino)phenyldimesitylborane (313220-01-8) → 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester (313220-10-9) + 1,3,5-trimethyl-benzene (108-67-8)

Guidance literature:

In benzene-d6; at 80 ℃; for 216h; under 3116.21 Torr; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1039/c5cc03072b

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + hydrogen (1333-74-0) + 2-(N,N-dimethylamino)phenyldimesitylborane (313220-01-8) → C10H12BNO4 + C35H44B2N2O2 + 2-(N,N-dimethylamino)phenylboronic acid dimethyl ester (313220-10-9) + 1,3,5-trimethyl-benzene (108-67-8)

Guidance literature:

In benzene-d6; at 80 ℃; for 216h; under 3420.23 Torr; Pressure; Solvent; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1039/c5cc03072b

upstream raw materials:

Trimethyl borate

N,N-dimethyl-aniline

carbon dioxide

hydrogen

Downstream raw materials:

2-(N,N-dimethylamino)phenyldimesitylborane

2-(N,N-dimethylamino)phenylboronic acid