N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Base Information

Chemical Name:N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine
CAS No.:208987-26-2
Molecular Formula:C₂₈H₄₀N₂O₁₁
Molecular Weight:580.632
Hs Code.:

Synonyms:N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Suppliers and Price of N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

There total 4 articles about N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 208987-25-1
[[(S)-2-tert-Butoxycarbonylamino-3-(4-tert-butoxycarbonyloxy-phenyl)-propionyl]-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-ylmethyl)-amino]-acetic acid ethyl ester

: 208987-26-2
N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Guidance literature:: With sodium hydroxide; water; In methanol; 1.) 0 deg C, 0.5 h, 2.) r.t., 3 h;

Reference yield:

: 4933-77-1
(3aR,5S,5aR,8aS,8bR)-2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-carbaldehyde

: 208987-26-2
N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) AcOH, 2.) NaBH₃CN / 1.) MeCN, 1 h, 2.) MeCN, overnight

2: 77 percent / BOP, HOBT, NMM, molecular sieves 4 Angstroem / CH₂Cl₂ / 36 h / Ambient temperature

3: 82 percent / NaOH, H₂O / methanol / 1.) 0 deg C, 0.5 h, 2.) r.t., 3 h

With 4-methyl-morpholine; sodium hydroxide; 4 A molecular sieve; water; sodium cyanoborohydride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol; acetic acid; In methanol; dichloromethane;

Reference yield:

: 20866-48-2
(S)-2-(tert-butoxycarbonylamino)-3-(4-(tert-butoxycarbonyloxy)phenyl)propanoic acid

: 208987-26-2
N-(tert-butoxycarbonyl)-L-tyrosyl-N-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactos-6-yl)glycine

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / BOP, HOBT, NMM, molecular sieves 4 Angstroem / CH₂Cl₂ / 36 h / Ambient temperature

2: 82 percent / NaOH, H₂O / methanol / 1.) 0 deg C, 0.5 h, 2.) r.t., 3 h

With 4-methyl-morpholine; sodium hydroxide; 4 A molecular sieve; water; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol; In methanol; dichloromethane;