2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide

Base Information

• Chemical Name: 2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide
• CAS No.: 72623-18-8
• Molecular Formula: C₁₄H₂₀NO₂*I
• Molecular Weight: 361.223
• Mol file: 72623-18-8.mol

Synonyms:2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide

Chemical Property of 2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide

There total 2 articles about 2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-(2-Methyl-3-methoxyphenyl)-4,4-dimethyl-2-oxazoline (72623-17-7) + methyl iodide (74-88-4) → 2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide (72623-18-8)

Guidance literature:

In nitromethane; at 70 ℃; for 22h;

DOI:10.1021/jo01294a035

Reference yield:

4,5-dihydro-2-(2',3'-dimethoxyphenyl)-4,4-dimethyloxazole (57598-32-0) → 2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide (72623-18-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / tetrahydrofuran / 168 h / Ambient temperature

2: 98 percent / nitromethane / 22 h / 70 °C

In tetrahydrofuran; nitromethane;

DOI:10.1021/jo01294a035

Reference yield: 95.0%

2-(3'-methoxy-o-tolyl)-4,4-dimethyl-N-methyl-2-oxazolinium iodide (72623-18-8) → 3-methoxy-2-methyl-benzaldehyde (56724-03-9)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 2h; Ambient temperature;

DOI:10.1021/jo01294a035

upstream raw materials:

2-(2-Methyl-3-methoxyphenyl)-4,4-dimethyl-2-oxazoline

methyl iodide

4,5-dihydro-2-(2',3'-dimethoxyphenyl)-4,4-dimethyloxazole

Downstream raw materials:

3-methoxy-2-methyl-benzaldehyde

biphenyl

3-bromo-3'-hydroxy-2',4-dimethyl-5-nitrostilbene

trans-3-bromo-4-iodomethyl-3'-methoxy-2'-methyl-5-nitrostilbene