(Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one

Base Information

• Chemical Name: (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one
• CAS No.: 1246401-08-0
• Molecular Formula: C₁₄H₁₆N₂O₃
• Molecular Weight: 260.293
• Mol file: 1246401-08-0.mol

Synonyms:(Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one

Chemical Property of (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one

There total 4 articles about (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

ethyl 2-[(1-methoxyethylidene)amino]acetate + 2,5-dimethoxybenzaldehyde (93-02-7) + methylamine (74-89-5) → (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one (1246401-08-0)

Guidance literature:

2,5-dimethoxybenzaldehyde; methylamine; With sodium sulfate; In chloroform; at 20 ℃; for 48h;

ethyl 2-[(1-methoxyethylidene)amino]acetate; at 20 ℃; for 24h;

DOI:10.1016/j.dyepig.2020.108258

Reference yield: 65.0%

methylamine (74-89-5) + (Z)-4-(2,5-dimethoxybenzylidene)-2-methyloxazol-5(4H)-one (782503-76-8) → (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one (1246401-08-0)

Guidance literature:

With potassium carbonate; In ethanol; water; for 4h; Reflux;

DOI:10.1021/jo2012384

Reference yield:

pyrrolidine (123-75-1) + methanol (67-56-1) + 2,5-dimethoxybenzaldehyde (93-02-7) + methylamine (74-89-5) → (Z)-4-(2,5-dimethoxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one (1246401-08-0)

Guidance literature:

pyrrolidine; 2,5-dimethoxybenzaldehyde; methylamine; With sodium sulfate; In chloroform; water; at 20 ℃; for 48h;

methanol; With ethyl ((methoxy)amino)acetate; at 20 ℃; for 24h;

DOI:10.1002/chem.201901151

upstream raw materials:

2,5-dimethoxybenzaldehyde

methylamine

(Z)-4-(2,5-dimethoxybenzylidene)-2-methyloxazol-5(4H)-one

pyrrolidine

Downstream raw materials:

(Z)-5-(2-hydroxy-5-methoxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one