4-fluorophenylvinylboronic acid

Base Information

Chemical Name:4-fluorophenylvinylboronic acid
CAS No.:1301266-96-5
Molecular Formula:C₈H₈BFO₂
Molecular Weight:165.96
Hs Code.:

Synonyms:4-fluorophenylvinylboronic acid

Suppliers and Price of 4-fluorophenylvinylboronic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-fluorophenylvinylboronic acid

Chemical Property:

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Technology Process of 4-fluorophenylvinylboronic acid

There total 6 articles about 4-fluorophenylvinylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 850567-55-4
2-(1-(4-fluorophenyl)vinyl)-4,4,5,5-tetramethyl-1,3-dioxa-2-borolane

: 1301266-96-5
4-fluorophenylvinylboronic acid

Guidance literature:: With sodium periodate; ammonium acetate; In water; acetone; at 80 ℃; for 2h; Reflux;
DOI:10.1016/j.tetlet.2021.153147

Reference yield:

: 405-99-2
para-fluorostyrene

: 1301266-96-5
4-fluorophenylvinylboronic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; lithium bromide; sodium periodate / 20 °C

2.1: potassium carbonate / methanol; tetrahydrofuran / 3 h / 20 °C

3.1: tert.-butyl lithium / diethyl ether; hexane / 0.5 h / -78 °C

3.2: -78 °C

4.1: hydrogenchloride / water / 2 h / 20 °C

With hydrogenchloride; sodium periodate; tert.-butyl lithium; potassium carbonate; acetic acid; lithium bromide; In tetrahydrofuran; methanol; diethyl ether; hexane; water;
DOI:10.1021/ja506579t

Reference yield:

: 350-35-6
1-(1,2-dibromoethyl)-4-fluorobenzene

: 1301266-96-5
4-fluorophenylvinylboronic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / methanol; tetrahydrofuran / 3 h / 20 °C

2.1: tert.-butyl lithium / diethyl ether; hexane / 0.5 h / -78 °C

2.2: -78 °C

3.1: hydrogenchloride / water / 2 h / 20 °C

With hydrogenchloride; tert.-butyl lithium; potassium carbonate; In tetrahydrofuran; methanol; diethyl ether; hexane; water;
DOI:10.1021/ja506579t