N'-(4-NITRO-PHENYL)-HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER

Base Information

• Chemical Name: N'-(4-NITRO-PHENYL)-HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER
• CAS No.: 92491-67-3
• Molecular Formula: C11H15 N3 O4
• Molecular Weight: 253.258
• Hs Code.: 2928000090
• Mol file: 92491-67-3.mol

Synonyms:Carbazicacid, 3-(p-nitrophenyl)-, tert-butyl ester (7CI);1-(tert-Butoxycarbonyl)-2-(4-nitrophenyl)hydrazine; tert-Butyl3-(p-nitrophenyl)carbazate

Chemical Property of N'-(4-NITRO-PHENYL)-HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 96.18000
• Density: 1.271g/cm³
• LogP: 3.43350

Purity/Quality:

99% ^*data from raw suppliers

N''-(4-Nitro-phenyl)-hydrazinecarboxylicacidtert-butylester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N'-(4-NITRO-PHENYL)-HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER

There total 7 articles about N'-(4-NITRO-PHENYL)-HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

di-tert-butyl dicarbonate (24424-99-5) + 4-nitrophenylhydrazone (100-16-3) → tert-butyl 2-(4-nitrophenyl)hydrazine-1-carboxylate (92491-67-3)

Guidance literature:

In acetonitrile; for 7h; Heating;

DOI:10.1021/ol052403f

Reference yield: 82.0%

di-tert-butyl dicarbonate (24424-99-5) + 4-nitrophenylhydrazine hydrochloride (636-99-7) → tert-butyl 2-(4-nitrophenyl)hydrazine-1-carboxylate (92491-67-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1039/c6nj03718f

Reference yield: 72.0%

tert-butyl N-tosyloxycarbamate (105838-14-0) + 4-nitro-aniline (100-01-6,104810-17-5) → tert-butyl 2-(4-nitrophenyl)hydrazine-1-carboxylate (92491-67-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 10 - 20 ℃; for 16h;

DOI:10.1055/s-0030-1261170

upstream raw materials:

N-(tert-butyloxycarbonyl) azide

4-nitrophenylhydrazone

di-tert-butyl dicarbonate

tert-butyl 2-(4-nitrophenyl)diazenecarboxylate

Downstream raw materials:

trans-4-nitrostilbene

2-(4-nitrophenyl)-1-benzofurane

tert-butyl 2-(4-(4’-fluorophenoxy)phenyl)azocarboxylate

para-nitrophenyl bromide

Refernces

• 1、 Halbig, Christian E.,Lasch, Roman,Krüll, Jasmin,Pirzer, Anna S.,Wang, Zhenping,Kirchhof, Jan N.,Bolotin, Kirill I.,Heinrich, Markus R.,Eigler, Siegfried. "Selective Functionalization of Graphene at Defect-Activated Sites by Arylazocarboxylic tert-Butyl Esters". supporting information. p. 3599 - 3603. Retrieved 2019/02/01.
• 2、 Zhang, Ji-Quan,Cao, Jun,Li, Wei,Li, Shu-Min,Li, Yong-Kang,Wang, Jian-Ta,Tang, Lei. "Palladium/copper-catalyzed arylation of alkenes with N′-acyl arylhydrazines". supporting information. p. 437 - 441. Retrieved 2017/02/05.