2-Fluoro-4-methoxybenzonitrile

Base Information

Chemical Name:2-Fluoro-4-methoxybenzonitrile
CAS No.:94610-82-9
Molecular Formula:C8H6 F N O
Molecular Weight:151.14
Hs Code.:2926909090
European Community (EC) Number:619-054-7
DSSTox Substance ID:DTXSID20348678
Nikkaji Number:J725.567E
Wikidata:Q72474024
Mol file:94610-82-9.mol

Synonyms:2-Fluoro-4-methoxybenzonitrile

Suppliers and Price of 2-Fluoro-4-methoxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
3-fluoro-4-cyanoanisole 98%
25g
$ 222.00

Ambeed
3-fluoro-4-cyanoanisole 98%
1g
$ 19.00

Ambeed
3-fluoro-4-cyanoanisole 98%
5g
$ 56.00

Crysdot
2-Fluoro-4-methoxybenzonitrile 98%
25g
$ 94.00

Matrix Scientific
2-Fluoro-4-methoxybenzonitrile 97%
25g
$ 93.00

Alichem
2-Fluoro-4-methoxybenzonitrile
1g
$ 1534.70

Alichem
2-Fluoro-4-methoxybenzonitrile
500mg
$ 855.75

Alichem
2-Fluoro-4-methoxybenzonitrile
250mg
$ 470.40

Alfa Aesar
2-Fluoro-4-methoxybenzonitrile, 97%
5g
$ 398.00

Alfa Aesar
2-Fluoro-4-methoxybenzonitrile, 97%
1g
$ 101.00

Total 66 raw suppliers

Chemical Property of 2-Fluoro-4-methoxybenzonitrile

Chemical Property:

Vapor Pressure:0.0545mmHg at 25°C
Melting Point:62-65℃
Boiling Point:233.9°Cat760mmHg
Flash Point:95.3°C
PSA：33.02000
Density:1.18g/cm³
LogP:1.70598
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:151.043341977
Heavy Atom Count:11
Complexity:174

Purity/Quality:

99%, ^*data from raw suppliers

3-fluoro-4-cyanoanisole 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 20/21/22-36/37/38
Safety Statements: 23-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C#N)F
Uses 2-Fluoro-4-methoxybenzonitrile is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

Technology Process of 2-Fluoro-4-methoxybenzonitrile

There total 12 articles about 2-Fluoro-4-methoxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 162101-31-7
(2-fluoro-4-methoxyphenyl)boronic acid

: 5-bromo-3-thiocyanatoindole

: 94610-82-9
2-fluoro-4-methoxyphenyl nitrile

Guidance literature:: With N,N,N-trimethyl-2-(sulfooxy)ethanaminium palladium(II) chloride; sodium carbonate; In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; water; for 2h;
DOI:10.1080/17415993.2018.1469632

Reference yield: 87.0%

: 3226-37-7
4-chlorophenyl thiocyanate

: 162101-31-7
(2-fluoro-4-methoxyphenyl)boronic acid

: 94610-82-9
2-fluoro-4-methoxyphenyl nitrile

Guidance literature:: With N,N,N-trimethyl-2-(sulfooxy)ethanaminium palladium(II) chloride; sodium carbonate; In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; water; for 2h;
DOI:10.1080/17415993.2018.1469632

Reference yield: 86.0%

: 557-21-1
zinc(II) cyanide

: 458-50-4
1-bromo-2-fluoro-4-methoxybenzene

: 94610-82-9
2-fluoro-4-methoxyphenyl nitrile

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; zinc; In N,N-dimethyl-formamide; at 120 ℃; for 16h; Inert atmosphere;
DOI:10.1021/jacs.1c05281