2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid

Base Information

Chemical Name:2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
CAS No.:126120-85-2
Molecular Formula:C8H4F2O4
Molecular Weight:202.114
Hs Code.:29329990
European Community (EC) Number:681-201-6
DSSTox Substance ID:DTXSID80378870
Nikkaji Number:J1.490.440I
Wikidata:Q72462501
Mol file:126120-85-2.mol

Synonyms:2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid;126120-85-2;2,2-Difluorobenzo[d][1,3]dioxole-4-carboxylic acid;2,2-Difluoro-1,3-benzodioxole-4-carboxylicacid;2,2-difluoro-2H-1,3-benzodioxole-4-carboxylic acid;MFCD01631473;2,3-(Difluoromethylenedioxy)benzoic acid;fludioxonil TP2;SCHEMBL977744;1,3-Benzodioxole-4-carboxylic acid, 2,2-difluoro-;Fludioxonil-TP CGA 192155;DTXSID80378870;AKOS005255430;CGA 192155;PB24729;AS-50429;CS-0055243;FT-0609227;EN300-95394;P10189;2,2-difluoro-1,3-dioxaindane-4-carboxylic acid;A805510;(2,2-difluoro-benzo(1,3)dioxol-4-carbocyclic acid;2,2-Difluorobenzo[d][1,3]dioxole-4-carboxylicacid;2,2-bis(fluoranyl)-1,3-benzodioxole-4-carboxylic acid;2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid, 97%;Z1269119885;2,2-DIFLUORO-BENZO[1,3]DIOXOLE-4-CARBOXYLIC ACID

Suppliers and Price of 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
250mg
$ 50.00

TRC
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
100mg
$ 45.00

SynQuest Laboratories
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid 98%
5 g
$ 117.00

SynQuest Laboratories
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid 98%
1 g
$ 37.00

Sigma-Aldrich
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid 97%
1g
$ 36.00

Matrix Scientific
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
5g
$ 72.00

Matrix Scientific
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
1g
$ 16.00

Frontier Specialty Chemicals
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid 97%
1g
$ 38.00

Frontier Specialty Chemicals
2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid 97%
5g
$ 150.00

Crysdot
2,2-Difluorobenzo[d][1,3]dioxole-4-carboxylicacid 97%
100g
$ 574.00

Total 35 raw suppliers

Chemical Property of 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid

Chemical Property:

Vapor Pressure:0.0061mmHg at 25°C
Melting Point:202-205 °C
Refractive Index:1.561
Boiling Point:260.8 °C at 760 mmHg
PKA:3.49±0.40(Predicted)
Flash Point:111.5 °C
PSA：55.76000
Density:1.66 g/cm³
LogP:1.70630
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:202.00776493
Heavy Atom Count:14
Complexity:256

Purity/Quality:

99%, ^*data from raw suppliers

2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,N,Xn
Statements: 36/37/38-50-41-22
Safety Statements: 26-36-61-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C2C(=C1)OC(O2)(F)F)C(=O)O

Technology Process of 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid

There total 2 articles about 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1583-59-1
2,2-difluoro-1,3-benzodioxole

: 124-38-9,18923-20-1
carbon dioxide

: 126120-85-2
2,2-difluoro-1,3-benzodioxole-4-carboxylic acid

Guidance literature:: 2,2-difluoro-1,3-benzodioxole; With sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -75 ℃; for 2h;

carbon dioxide; In tetrahydrofuran; cyclohexane; at -78 ℃; Further stages.;
DOI:10.1002/1099-0690(200102)2001:4<691::AID-EJOC691>3.0.CO;2-A