methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Base Information

Chemical Name:methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate
CAS No.:112938-17-7
Molecular Formula:C₂₅H₂₈N₂O₃S
Molecular Weight:436.575
Hs Code.:

Synonyms:methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Suppliers and Price of methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

There total 19 articles about methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 848302-21-6
methyl 6-[(3S,7R,7aR)-6-benzyl-5-oxo-3-phenyltetrahydro-5H-imidazo[1,5-c][1,3]thiazol-7-yl]-6-oxohexanoate

: 112938-17-7
methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Guidance literature:: methyl 6-[(3S,7R,7aR)-6-benzyl-5-oxo-3-phenyltetrahydro-5H-imidazo[1,5-c][1,3]thiazol-7-yl]-6-oxohexanoate; With acetic acid; zinc; at 80 ℃; for 5h;

With piperidine; at 100 ℃; for 1.5h;
DOI:10.1021/jo0488107

Reference yield:

: 67-56-1
methanol

: 5-[(3aS,6aR)-1,3-dibenzyl-2-oxo-tetrahydro-1H-thieno[3,4-d]imidazol-4-ylidene]pentanoic acid

: 112938-17-7
methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Guidance literature:: With sulfuric acid; at 55 ℃; for 4h; Sonication;

Reference yield:

: 848302-22-7
(3S,7aR)-6-benzyl-7-hydroxy-3-phenyltetrahydro-5H-imidazo[1,5-c][1,3]thiazol-5-one

: 112938-17-7
methyl (5Z)-5-[(3aS,6aR)-1,3-dibenzyl-2-oxohexahydro-4H-thieno[3,4-d]imidazol-4-ylidene]pentanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: 98 percent / BF₃*Et₂O / CH₂Cl₂ / 0.17 h / 0 °C

2.1: 70 percent / KOH; tert-butyl hydrogen peroxide / H₂O; methanol / 0.5 h

3.1: 0.630 g / diethyl ether / 0.17 h

4.1: zinc; acetic acid / 5 h / 80 °C

4.2: 70 percent / piperidine / 1.5 h / 100 °C

With tert.-butylhydroperoxide; potassium hydroxide; boron trifluoride diethyl etherate; acetic acid; zinc; In methanol; diethyl ether; dichloromethane; water; 2.1: Baeyer-Villiger oxidation;
DOI:10.1021/jo0488107