N-phenylacetylanthranilic acid ethyl ester

Base Information

• Chemical Name: N-phenylacetylanthranilic acid ethyl ester
• CAS No.: 174575-70-3
• Molecular Formula: C₁₇H₁₇NO₃
• Molecular Weight: 283.327
• Mol file: 174575-70-3.mol

Synonyms:N-phenylacetylanthranilic acid ethyl ester

Chemical Property of N-phenylacetylanthranilic acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-phenylacetylanthranilic acid ethyl ester

There total 2 articles about N-phenylacetylanthranilic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

phenylacetyl chloride (103-80-0) + 2-ethoxycarbonylaniline (87-25-2) → N-phenylacetylanthranilic acid ethyl ester (174575-70-3)

Guidance literature:

With potassium carbonate; In dichloromethane; at 15 ℃;

DOI:10.1016/0040-4020(95)01035-1

Reference yield: 18.0%

ethanol (64-17-5) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) + phenylacetylene (536-74-3) → N-phenylacetylanthranilic acid ethyl ester (174575-70-3)

Guidance literature:

With oxygen; potassium carbonate; copper(l) chloride; In acetonitrile; at 20 - 28 ℃; for 12h; under 760.051 Torr; regioselective reaction; Irradiation; Green chemistry;

DOI:10.1039/c9gc03608c

Reference yield: 79.0%

oxalyl dichloride (79-37-8) + N-phenylacetylanthranilic acid ethyl ester (174575-70-3) → 2-{4,5-Dioxo-2-[1-phenyl-meth-(Z)-ylidene]-oxazolidin-3-yl}-benzoic acid ethyl ester

Guidance literature:

In acetonitrile; for 1h;

DOI:10.1016/0040-4020(95)01035-1

upstream raw materials:

phenylacetyl chloride

2-ethoxycarbonylaniline

ethanol

anthranilic acid

Downstream raw materials:

3-phenyl-quinoline-2,4-diol