4-Trimethylsilyl-3-butyn-2-ol

Base Information

Chemical Name:4-Trimethylsilyl-3-butyn-2-ol
CAS No.:6999-19-5
Molecular Formula:C₇H₁₄OSi
Molecular Weight:142.273
Hs Code.:29319090
European Community (EC) Number:628-368-3
DSSTox Substance ID:DTXSID00990235
Nikkaji Number:J846.033G
Mol file:6999-19-5.mol

Synonyms:4-TMS-3-butyn-2-ol;4-trimethylsilyl-3-butyn-2-ol

Suppliers and Price of 4-Trimethylsilyl-3-butyn-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
4-Trimethylsilyl-3-butyn-2-ol >97.0%(GC)
5g
$ 64.00

Sigma-Aldrich
4-(Trimethylsilyl)-3-butyn-2-ol 97%
25g
$ 231.00

Sigma-Aldrich
4-(Trimethylsilyl)-3-butyn-2-ol 97%
5g
$ 71.50

Frontier Specialty Chemicals
4-Trimethylsilyl-3-butyn-2-ol 97%
5g
$ 71.00

Crysdot
4-(Trimethylsilyl)but-3-yn-2-ol 95+%
100g
$ 434.00

Chem-Impex
4-Trimethylsilyl-3-butyn-2-ol,97%(GC) 97%(GC)
5G
$ 63.84

Chemenu
4-(trimethylsilyl)but-3-yn-2-ol 95%
100g
$ 406.00

American Custom Chemicals Corporation
(+/-) 4-TRIMETHYLSILYL-3-BUTYN-2-OL 95.00%
10G
$ 514.00

American Custom Chemicals Corporation
(+/-) 4-TRIMETHYLSILYL-3-BUTYN-2-OL 95.00%
5G
$ 457.00

Ambeed
4-(Trimethylsilyl)but-3-yn-2-ol 98%
25g
$ 422.00

Total 32 raw suppliers

Chemical Property of 4-Trimethylsilyl-3-butyn-2-ol

Chemical Property:

Vapor Pressure:0.477mmHg at 25°C
Refractive Index:n 20/D 1.446
Boiling Point:170.2 °C at 760 mmHg
PKA:13.78±0.20(Predicted)
Flash Point:56.8 °C
PSA：20.23000
Density:0.883 g/cm³
LogP:1.24800
Storage Temp.:2-8°C
Solubility.:highly soluble in all standard organic solvents (hexanes, toluene, CH2Cl2, EtOAc, alcohols, ethers). Partially soluble in water.
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:142.081391600
Heavy Atom Count:9
Complexity:143

Purity/Quality:

≥98.0% ^*data from raw suppliers

4-Trimethylsilyl-3-butyn-2-ol >97.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C#C[Si](C)(C)C)O
Physical properties bp 83–85°C (13 mmHg).
Uses More recently, Mulzer has reported use of the corresponding allenylsilane derived from 4-TMS-3-butyn-2-ol for use in the synthesis of the C13–C18 fragment of branimycin (eq 2).

Technology Process of 4-Trimethylsilyl-3-butyn-2-ol

There total 31 articles about 4-Trimethylsilyl-3-butyn-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5930-98-3
4-trimethylsilyl-3-butyn-2-one

: 6999-19-5,103253-60-7,121522-26-7,121522-27-8
(S)-4-trimethylsilyl-3-butyn-2-ol

Guidance literature:: With potassium hydroxide; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide; In isopropyl alcohol; at 28 ℃; for 12h;
DOI:10.1021/ja971570a

Reference yield: 95.0%

: 75-77-4
chloro-trimethyl-silane

: 2028-63-9
but-3-yn-2-ol

: 103253-60-7,121522-26-7,121522-27-8,6999-19-5
4-trimethylsilyl-3-butyn-2-ol

Guidance literature:: but-3-yn-2-ol; With ethylmagnesium bromide; In tetrahydrofuran;

chloro-trimethyl-silane; In tetrahydrofuran; for 2h; Heating;
DOI:10.1002/hlca.200290002