5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

Base Information

• Chemical Name: 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine
• CAS No.: 865479-43-2
• Molecular Formula: C₁₇H₁₅BF₂N₂
• Molecular Weight: 296.127

Synonyms:5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

Chemical Property of 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

There total 4 articles about 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

2-methyl-1H-pyrrole (636-41-9) + boron trifluoride diethyl etherate (109-63-7) + benzoyl chloride (98-88-4) → 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine (865479-43-2)

Guidance literature:

2-methyl-1H-pyrrole; benzoyl chloride; In 1,2-dichloro-ethane; at 20 ℃; for 12.5h; Inert atmosphere;

With triethylamine; In 1,2-dichloro-ethane; at 0 ℃; for 0.333333h; Inert atmosphere;

boron trifluoride diethyl etherate; In 1,2-dichloro-ethane; for 1h; Inert atmosphere; Reflux;

Reference yield: 35.0%

hydrogenchloride (7647-01-0,15364-23-5) + 4,5,6,7-tetrahydro-2H-isoindole (51649-35-5) + 4,4-difluoro-3,5-dimethyl-8-(4-formylphenyl)-4-bora-3a,4a-diaza-s-indacene (1162642-41-2) → 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine (865479-43-2) + C36H32N4H2((C6H4C(C4H2NCH3)2)BF2)4*2HCl

Guidance literature:

In dichloromethane; (N2, shielded from light) isoindole-compound and aldehyde-compound were added to CH2Cl2, stirred under N2 for 10 min, BF3*O(C2H5)2 was added, stirred for 2.5 h, DDQ was added, stirred for 18 h; the soln. was washed with 10% aq. Na2SO4 and brine, dried (MgSO4), filtered, concd. in vac., column chromy. on silica gel, CH2Cl2, CH2Cl2-THF (20:1), washed with 5% aq. HCl and water, dried (MgSO4), filtered, rotary evapd., crystd. from CH2Cl2-O(C2H5)2;

DOI:10.1021/ja108493b

Reference yield: 17.0%

2-methyl-1H-pyrrole (636-41-9) + boron trifluoride diethyl etherate (109-63-7) + benzaldehyde (100-52-7) → 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine (865479-43-2)

Guidance literature:

2-methyl-1H-pyrrole; benzaldehyde; With trifluoroacetic acid; In dichloromethane; for 12h; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

boron trifluoride diethyl etherate; With triethylamine; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.202012764

upstream raw materials:

hydrogenchloride

4,5,6,7-tetrahydro-2H-isoindole

4,4-difluoro-3,5-dimethyl-8-(4-formylphenyl)-4-bora-3a,4a-diaza-s-indacene

2-methyl-1H-pyrrole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 865479-43-2 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

Send

Send

Metric Ton KG G Pound L ML

Send

Send